CHARACTERIZATION OF MUTAGENIC PRINCIPLES AND CARCINOGENICITY TEST OF DILL WEED AND SEEDS
スポンサーリンク
概要
- 論文の詳細を見る
Among the various kinds of spices tested, the aqueous extracts of dill weed from Anethum graveolens L. and dill seeds from A. sowa D.C. (Umbelliferae), exhibited a mutagenicity to Salmonella typhimurium, strains TA98 and TA100. The aqueous methanol extracts were fractionated by the mutation assay using the strain TA98 with S-9 Mix. Isorhamnetin 3-sulfate (persicarin) and quercetin 3-sulfate were characterized as the mutagenic principles. Carcinogenicity was not observed for dill weed and seeds when the diets containing these in 33% were administered for 450 and 410 days, respectively, to the inbred strain ACI rats.
- 公益社団法人日本薬学会の論文
著者
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HIRONO Iwao
Second Department of Pathology
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YOSHIHIRA Kunitoshi
National Institute of Hygienic Sciences
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HIRONO Iwao
Department of Pathology, Fujita-Gakuen University School of Medicine
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NATORI SHINSAKU
National Institute of Hygienic Sciences
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Hosaka Shigetoshi
Department Of Carcinogenesis And Cancer Susceptibility Institute Of Medical Science University Of To
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Fukuoka Masamichi
National Institute Of Hygienic Sciences
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Hirono Iwao
Department Of Carcinogenesis And Cancer Susceptibility Institute Of Medical Science University Of To
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Sakamoto Kyoko
Hatano Research Institute Food And Drug Safety Center
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IWAHARA SHIGEO
Hatano Research Institute, Food and Drug Safety Center
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Natori Shinsaku
National Institute Of Hygienic Sciences:(present Address)meiji College Of Pharmacy
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Hirono I
Second Department Of Pathology
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Iwahara Shigeo
Hatano Research Institute Food And Drug Safety Center
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Yoshihira Kunitoshi
National Institute Of Health Sciences (formerly National Institute Of Hygienic Sciences)
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YOSHIHIRA KUNITOSHI
National Institute of health Sciences
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