QUANTITATIVE DETERMINATION OF THE SUPEROXIDE RADICALS IN THE XANTHINE OXIDASE REACTION BY MEASUREMENT OF THE ELECTRON SPIN RESONANCE SIGNAL OF THE SUPEROXIDE RADICAL SPIN ADDUCT OF 5,5-DIMETHYL-1-PYRROLINE-1-OXIDE
スポンサーリンク
概要
- 論文の詳細を見る
Reactivities of biologically active compounds with superoxide radicals were examined by measurement of electron spin resonance (ESR) spectra of 5-hydroperoxy-2,2-dimethy 1-1-pyrrolidinyloxyl formed from 5,5-dimethyl-1-pyrroline-1-oxide and the superoxide radicals generated by xanthine-xanthine oxidase system. Quantitative determination of the superoxide rachcals was performed by comparing the intensity of the spin adducts with chat of 4-hydroxy-2,2,6,6-tetramethyl-pipperi-dinooxyl whose spin concentration was determined. Methyl viologen enhanced the formation of this spin adducts, while, rutin and luteoskyrin prevented it.
- 公益社団法人日本薬学会の論文
著者
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Kohno M
Dainippon Screen Manufacturing Co. Ltd. Kyoto Jpn
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Kohno M
Jeol Ltd. Tokyo
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Kohno M
Analytical Instruments Division Jeol Ltd.
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HIRONO Iwao
Second Department of Pathology
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HIRONO Iwao
Department of Pathology, Fujita-Gakuen University School of Medicine
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Kohno M
Esr Application Laboratory Application And Research Center Analytical Instruments Division Jeol Ltd.
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Ueno I
Sci. Univ. Tokyo
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Hirono I
Department Of Carcinogenesis And Cancer Susceptibility Institute Of Medical Science University Of To
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Hirono Iwao
Department Of Carcinogenesis And Cancer Susceptibility Institute Of Medical Science University Of To
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UENO IKUKO
ESR Application Laboratory, JEOL Ltd.
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KOHNO MASAHIRO
Division of Environmental Chemistry, National Institute of Hygienic Sciences
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YOSHIHIRA KUNITOSHI
Yoga, Setagaya-ku, Tokyo
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Yoshihira Kunitoshi
Yoga Setagaya-ku Tokyo
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Hirono I
Second Department Of Pathology
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