CHEMICAL AND TOXICOLOGICAL STUDIES ON BRACKEN FERN, PTERIDIUM AQUILINUM VAR. LATIUSCULUM. IV. SURVEYS ON BRACKEN CONSTITUENTS BY MUTAGEN TEST
スポンサーリンク
概要
- 論文の詳細を見る
Among the twenty-three compounds isolated from bracken, kaempferol showed noticeable mutagenicity to Salmonella typhimurium, strains TA 100 and TA 98,with S-9 mix. With pretreatment of 'hesperidinase' the mutagenic activity of the boiling water extract was concentrated to the fraction containing astragalin. Several extracts and fractions were prepared for test of mutagenicity and the presence of other mutagens in bracken besides flavonoids was evidenced.
- 公益社団法人日本薬学会の論文
著者
-
SUGIMURA Takashi
Biochemistry Division, National Cancer Center Research Institute
-
NATORI SHINSAKU
National Institute of Hygienic Sciences
-
Fukuoka Masamichi
National Institute Of Hygienic Sciences
-
Natori Shinsaku
National Institute Of Hygienic Sciences:(present Address)meiji College Of Pharmacy
-
Sugimura Takashi
Biochemistry Division National Cancer Center Research Institute
-
Sugimura Takashi
Biochemistry Division National Cancer Center
関連論文
- Induction of multinucleated cells and apoptosis in the PC-3 prostate cancer cell line by low concentrations of polyethylene glycol 1000
- Mouse strain differences in inflammatory responses of colonic mucosa induced by dextran sulfate sodium cause differential susceptibility to PhIP-induced large bowel carcinogenesis
- Toxicogenomic approach to the prediction of carcinogenic potentials of heterocyclic amines in rat colon(Analysis of Toxicological Mechanisms : A Toxicogenomics Approach, Proceedings of the 32nd Annual Meeting)
- Differential gene expression profiles in colon epithelium of two rat strains with distinct susceptibility to colon carcinogenesis after exposure to PhlP in combination with dietary high fat
- Parp-1 deficiency implicated in colon and liver tumorigenesis induced by azoxymethane
- Induction of Intestinal Tumors and Lymphomas in C57BL/6N Mice by a Food-borne Carcinogen, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
- Frequent and Multiple Mutations at Minisatellite Loci in Sporadic Human Colorectal and Gastric Cancers : Possible Mechanisble Mechanistic Differences from Microsatellite Instability in Cancer Cells
- Helicobacter pylori Extracts Exhibit Nicotinamide Adenine Dinucleotide-derived Adenylation but Not Mono(adenosine 5'-diphosphate-ribosyl)ation of DNA Ligase
- Isolation and Cloning of Rat Poly (ADP-Ribose) Glycohydrolase: Presence of a Potential Nuclear Export Signal Conserved in Mammalian Orthologs
- Linkage Maping of the Rat Poly(ADP-ribose) Glycohydrolase (Parg) Gene to Chromosome 16
- Presence in Pieris rapae of Cytotoxic Activity against Human Carcinoma Cells
- Inactivation of Pyrolysate Mutagens by Nitrite and by Chlorinated Tap Water (Regular Presentations) (Proceedings of the 8th Symposium on Environmental Pollutants and Toxicology)
- CHEMICAL AND TOXICOLOGICAL STUDIES ON BRACKEN FERN, PTERIDIUM AQUILINUM VAR. LATIUSCULUM. IV. SURVEYS ON BRACKEN CONSTITUENTS BY MUTAGEN TEST
- Stability of centrosome numbers in poly(ADP-ribose) polymerase-1- and poly(ADP-ribose) glycohydrolase-deficient mouse ES cells
- Lack of altered frequency of sister-chromatid exchanges in poly(ADP-ribose) glycohydrolase-deficient mouse ES cells treated with methylmethanesulfonate
- Poly(ADP-ribose) polymerase-1 gene in human tumor cell lines: Its expression and structural alteration
- Developmental changes of poly(ADP-ribose) polymerase expression in Sarcophaga peregrina
- CHEMICAL AND TOXICOLOGICAL STUDIES ON BRACKEN FERN, PTERIDIUM AQUILINUM VAR. LATIUSCULUM. VIII. THE INABILITY OF BRACKEN EXTRACTS CONTAINING PTEROSINS TO CAUSE CATTLE BRACKEN POISONING
- CHARACTERIZATION OF MUTAGENIC PRINCIPLES AND CARCINOGENICITY TEST OF DILL WEED AND SEEDS
- VISCOMETRIC ANALYSIS OF EFFECTS OF CYTOCHALASANS ON IN VITRO POLYMERIZATION AND DEPOLYMERIZATION OF MICROTUBULES
- Disposition and Metabolism of 2-Nitro-p-cresol in Rats and Its Effect on Hepatic Ornithine Decarboxylase (Proceedings of the 12 th Symposium on Environmental Pollutants and Toxicology) (Regular Presentations)
- Hyperploidy of embryonic fibroblasts derived from Parp-1 knockout mouse
- Mechanism of Testicular Damage by Phthalic Acid Esters (Proceedings of the 20th Symposium on Toxicology and Environmental Health)
- Inhibition of poly(ADP-ribose) glycohydrolase activity by cyclic peptide antibiotics containing piperazic acid residues
- Phylogenic distribution of poly(ADP-ribose) glycohydrolase and poly(ADP-ribose)-digesting phosphodiesterase
- Establishment of poly(ADP-ribose) polymerase-deficient mouse embryonic stem cell lines
- Impairment in S-phase entry of splenocytes of Parp-1 knockout mice
- B-14-3 New Triterpenoids of the Rearranged Hopane Series from Ferns(Terpenoids)
- Metabolism of Musk Xylene (MX) in Rats (Proceedings of the 16 th Symposium on Environmental Pollutants and Toxicology)
- Purification and characterization of poly(ADP-ribose) polymerase from Sarcophaga peregrina
- VARIETY OF PHENOTYPICAL EXPRESSION OF INTESTINAL MARKER ENZYMES AND MUCIN IN HUMAN STOMACH INTESTINAL METAPLASIA
- Chemical and Pharmacological Studies on the Constituents of Loranthus pentandrus
- Mutagenicity of flavone derivatives.
- Atrophy of salivary glands and pancreas of rats fed on diet with amino-methyl-.ALPHA.-carboline.
- Chemical synthesis of 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ), a potent mutagen isolated from broiled fish.
- Potent novel mutagens produced by broiling fish under normal conditions.
- Induction of tumors in the forestomach and liver of mice by feeding 2-amino-3,4-dimethylimidazo(4,5-f)quinoline (MeIQ).:MeIQ
- Norharman and Harman in Human Urine.
- Mutagen Formation after Heating of Mixtures of Guanidino Compounds, Amino Acids and Glucose.
- Isolation and Cloning of Rat Poly(ADP-Ribose) Glycohydrolase: Presence of a Potential Nuclear Export Signal Conserved in Mammalian Orthologs.