Morphological, chemical and molecular biological comparison among Artemisia capillaris, A. japonica and their natural hybrids
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概要
- 論文の詳細を見る
The heads of Artemisia capillaris have been used for medicinal purposes, as their choleretic effect of capillarisin (CAP) and 6,7-dimethylesculetin (DME) are known. However, hybrid plants between A. capillaris and A. japonica are often found in the crude drugs sold in the Japanese market, therefore observation of flowering dates, the ten morphological characteristics of flower heads, and CAP and DME contents, as well as RAPD (Random Amplified Polymorphic DNA) analysis were carried out for A. capillaris, A. japonica and their natural hybrid plants grown in the flood plain of the Sho-river, Takaoka, Toyama, Japan. Further, the pharmaceutical status of flower heads derived from the hybrid plants was discussed. The results showed that hybrid plants were similar to A. japonica, and when flower heads from the hybrid plants were mixed in crude drugs, the quality of the crude drug could decline because of traces of CAP and DME. Flower heads of hybrid plants could be detected with certainly by the presence of secretory sacs on corolla lobes of disk flowers and lower content of CAP and DME and removed.
- 日本生薬学会の論文
- 2003-02-20
著者
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Mia Md.
Tsukuba Medicinal Plant Research Station National Institute Of Health Sciences
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SATAKE Motoyoshi
National Institute of Health Sciences
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MINAMI Motoyasu
Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences
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SHIBATA Toshiro
Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences
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Kayano Toshiaki
Department Of Biotechnology National Institute Of Agrobiological Resources
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Shibata T
Tsukuba Medicinal Plant Research Station National Institute Of Health Sciences
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Sakai Eiji
Tsukuba Medicinal Plant Research Station National Institute Of Health Sciences
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Oka Kenji
Central Research Laboratory Kotaro Pharmaceutical Co. Ltd.
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Kondo Seizo
Central Research Laboratory Kotaro Pharmaceutical Co. Ltd.
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Hosokawa Keizo
Tsukuba Medicinal Plant Research Station National Institute Of Health Sciences
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Tanaka Hiroshi
Department Of Cardiology Jichi Medical School
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MINAMI Motoyasu
Department of Environmental Biology, College of Bioscience and Biotechnology, Chubu University
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Hosokawa Keizo
Department Of Nutritional Management Faculty Of Health Sciences Hyogo University
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Oka Kenji
Research Laboratory Kotaro Pharmaceutical Co. Ltd.
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Minami Motoyasu
Department Of Environmental Biology College Of Bioscience And Biotechnology Chubu University
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Koga-ban Yasunori
Department Of Biotechnology National Institute Of Agrobiological Resources
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Satake M
National Institute Of Health Sciences:(present Office)japan Pharmacist Education Center
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Shibata Toshiro
Tsukuba Medicinal Plant Research Station National Institute Of Health Sciences
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Tanaka Hiroshi
Department Of Analytical Chemistry Faculty Of Pharmaceutical Sciences Hoshi University
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Tanaka Hiroshi
Department Of Biotechnology National Institute Of Agrobiological Resources
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