Effect of Magnesium, Strontium or Fluoride Ions on in vitro Activities of Odontoblast-like Cells (MDPC-23)
スポンサーリンク
概要
- 論文の詳細を見る
Magnesium (Mg), strontium (Sr) or fluoride (F) ions have been shown to affect in vitro activities of bone cells and in vivo mineralization. The purpose of this study was to investigate the effect of Mg, Sr and F ions on the activities of odontoblast-like cells (MDPC-23) using an in vitro cell culture model. Mg, Sr or F ions were added to the medium in the following concentrations : Mg-1, 5, 10mM; Sr-0.05, 0.1, 0.3, 1mM; F-0.005, 0.01, 0.05, 0.1mM. Results were observed after 1, 7 and 14 days using Von Kossa staining, scanning and transmission electron microscopy. Preliminary results showed the following : Mg ions demonstrated a positive effect at low concentrations and a negative effect at high concentrations; Sr ions demonstrated a positive dose dependent effect up to a concentration of 0.1mM and a negative effect at higher concentrations; and F ions demonstrated a positive dose-dependent effect up to a concentration of 0.005mM and inhibitory effects at higher concentrations. This preliminary study showed that the positive or negative effects of Mg, Sr or F ions on odontoblastic activities (proliferation and mineralization) depend on their concentration levels in the environment.
- 硬組織再生生物学会の論文
著者
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LEGEROS Racquel
ニューヨーク大学
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Nagatsuka Hitoshi
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry & Pharmaceutical S
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Nagai Noriyuki
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry & Pharmaceutical S
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Inoue Masahisa
Laboratories for Structure and Function Research, Faculty of Pharmaceutical Sciences, Tokushima Bunr
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Inoue Miho
Department of Biomaterials and Biomimetics, College of Dentistry, New York University
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Inoue Masahisa
Laboratories For Structure And Function Research Faculty Of Pharmaceutical Sciences Tokushima Bunri
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Inoue Masahisa
徳島文理大学 薬学部機能形態学
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Legeros Racquel
Department Of Biomaterials And Biomimetics New York University College Of Dentistry
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Legeros Racquel
Department Of Biomaterials And Biomimetics College Of Dentistry New York University
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Legeros Racquel
日本大学松戸歯学部 組織・発生・解剖学講座
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Rui Kan
Department of Oral Pathology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Ok
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Nagatsuka Hitoshi
Department Of Oral Pathology And Medicine Graduate School Of Medicine And Dentistry Okayama Universi
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Nagai Noriyuki
Department Of Oral Pathology And Medicine Dental School Okayama University
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Rui Kan
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry And Pharmaceutical S
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Rui Kan
Department Of Oral Pathology And Medicine Okayama University Graduate School Of Medicine Dentistry A
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Rohanizadeh Ramin
Department of Biomaterials & Biomimetics, New York University College of Dentistry
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Guo Liang
Department of Periodontology, New York University College of Dentistry
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Davidson Robert
Department of Periodontology, New York University College of Dentistry
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Guo Liang
Department Of Periodontology New York University College Of Dentistry
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Rohanizadeh Ramin
Department Of Biomaterials & Biomimetics New York University College Of Dentistry
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Davidson Robert
Department Of Periodontology New York University College Of Dentistry
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Inoue Masahisa
Department Of Oral Pathology And Medicine Okayama University Graduate School Of Medicine Dentistry A
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Nagai Noriyuki
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry And Pharmaceutical S
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Inoue Masahisa
Department Of Biomaterials And Biomimetics College Of Dentistry New York University
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Inoue Masahisa
Department Of Oral Pathology And Medicine Okayama University Graduate School Of Medicine Dentistry A
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Inoue Masahisa
Laboratories For Structure And Function Research Faculty Of Pharmaceutical Sciences Tokushima Bunri
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