Wnt5a Gene Plays a Role in Mouse Embryonic Orofacial Development(International Symposium of Maxillofacial & Oral Regenerative Biology in OKAYAMA 2005)
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概要
- 論文の詳細を見る
To determine if Wnt5a gene involved in orofacial development, especially secondary palate development, we checked Wnt5a protein and mRNA in wild-type mouse embryos, and also searched Wnt5a knockout mice palates. We found Wnt5a is expressed during orofacial development, especially necessary for normal secondary palate and tongue morphogenesis. Wnt5a deficient mice exhibit cleft palate and abnormal distortion tongue suggests Wnt5a is essential to the palate development. Our data suggested that defection of MEE proliferation in Wnt5a (-/-) secondary palate indicates Wnt5a gene may regulate palate growth.
- 硬組織再生生物学会の論文
著者
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長塚 仁
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry & Pharmaceutical
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長塚 仁
岡山大学大学院医歯薬学総合研究科病態機構学講座口腔病理学分野
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長塚 仁
岡山大学 大学院医歯薬学総合研究科消化器腫瘍外科
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長塚 仁
岡山大学大学院医歯学総合研究科口腔病理病態学講座
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Xiao Jing
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry & Pharmaceutical S
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Nagatsuka Hitoshi
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry & Pharmaceutical S
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Nagai Noriyuki
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry & Pharmaceutical S
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Zhu En-xin
Department Of Oral Biology College Of Stomatology Dalian Medical University
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Zhu En-xin
Department Of Oral Pathology College Of Stomatology Dalian Medical University
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Xiao Jing
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry & Pharmaceutical
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Xiao Jing
Department Of Oral Biology College Of Stomatology Dalian Medical University
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Zhu En
Department Of Oral Pathology College Of Stomatology Dalian Medical University
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Gunduz Mehmet
Department Of Otolaryngology Head And Neck Surgery Wakayama Medical University
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Nagatsuka Hitoshi
Department Of Oral Pathology And Medicine Graduate School Of Medicine And Dentistry Okayama Universi
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Nagai Noriyuki
Department Of Oral Pathology Okayama University Dental School
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Nagai Noriyuki
Department Of Oral Pathology And Medicine Dental School Okayama University
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Li Changgong
Department of Pediatrics, Keck School of Medicine, University of Southern California
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Minoo Parviz
Department of Pediatrics, Keck School of Medicine, University of Southern California
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Xiao Jing
Department Of Oral Pathology College Of Stomatology Dalian Medical University:department Of Oral Pat
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Xiao Jing
Department Of Oral Pathology Graduate School Of Medicine Dentistry And Pharmaceutical Sciences Okaya
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Gunduz Mehmet
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry And Pharmaceutical S
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Nagai Noriyuki
Dept. Of Oral Pathology Okayama Univ. Dental School.
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Minoo Parviz
Department Of Pediatrics Keck School Of Medicine University Of Southern California
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Li Changgong
Department Of Pediatrics Keck School Of Medicine University Of Southern California
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Gunduz Mehmet
岡山大学大学院医歯学総合研究科病態機構学講座:口腔病理病態学分野
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Nagai Noriyuki
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry And Pharmaceutical S
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Nagai Noriyuki
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry And Pharmaceutical S
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Xiao Jing
Department Of Oral Pathology College Of Stomatology Dalian Medical University:department Of Oral Pat
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