Immunohistochemical Characteristics of Odontogenic Neoplasms and Their Physiological Counterparts
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概要
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Development of the tooth is a complex and fascinating set of processes which require a sequential integration of numerous biological steps. For dental doctors, interest is particularly high, because the tooth is mainly composed of surface ectodermal epithelium and neural crest derived neuroectodermal mesenchyma, and formed by epithelial-mesenchymal interactions. There are many different types of odontogenic neoplasms. In general, proliferation, development and cytological differentiation of the neoplastic cells reflect the normal physiological development of the outbreak mother cells and/or tissues. There would appear to be a relationship between the cytological differentiation of odontogenic neoplastic cells and the physiological development and differentiation of tooth germ. We describe some morphogenesis regulation factors, such as Notch signaling, in the odontogenic neoplastic cells, in both well-differentiated and poorly-differentiated neoplasms. Our results suggest that these factors play some role in cytological differentiation or acquisition of tissue-specific characteristics in neoplastic cells.
著者
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長塚 仁
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry & Pharmaceutical
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長塚 仁
岡山大学大学院医歯薬学総合研究科病態機構学講座口腔病理学分野
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長塚 仁
岡山大学 大学院医歯薬学総合研究科消化器腫瘍外科
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長塚 仁
岡山大学大学院医歯学総合研究科口腔病理病態学講座
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Nagatsuka Hitoshi
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry & Pharmaceutical S
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Katase Naoki
Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry & Pharmaceutical S
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Siar Chong
Department Of Oral Pathology Oral Medicine & Periodontology Faculty Of Dentistry University Of M
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Hidetsugu Tsujigiwa
Department Of Virology Graduate School Of Medicine Dentistry And Pharmaceutical Sciences Okayama Uni
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Tsujigiwa Hidetsugu
徳島文理大学 薬学部機能形態学
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Tsujigiwa Hidetsugu
Department Of Oral Pathology And Medicine Graduate School Of Medicine & Dentistry Okayama Univer
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Komori Toshifumi
Hard Tissue Pathology Unit Matsumoto Dental University Graduate School Of Oral Medicine
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Katase Naoki
Department Of Oral Pathology And Medicine Okayama University Graduate School Of Medicine Dentistry A
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Nakano Keisuke
Hard Tissue Pathology Unit Matsumoto Dental University Graduate School Of Oral Medicine
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Gunduz Mehmet
Department Of Otolaryngology Head And Neck Surgery Wakayama Medical University
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Kawakami Toshiyuki
Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine
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Nagatsuka Hitoshi
Department Of Oral Pathology And Medicine Graduate School Of Medicine And Dentistry Okayama Universi
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Kawakami Toshiyuki
Hard Tissue Pathology Unit Matsumoto Dental University Graduate School Of Oral Medicine
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Tujigiwa Hidetugu
Department Of Oral Pathology And Medicine Graduate School Of Medicine And Dentistry Okayama Universi
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Tsujigiwa Hidetsugu
Department Of Oral Pathology And Medicine Graduate School Of Medicine And Dentistry. Okayama Univers
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Siar Chong-huat
Malaya Univ. Dept. Of Oral Pathology
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Katase Naoki
Departments Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry And Pharmaceutical
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Gunduz Mehmet
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry And Pharmaceutical S
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Gunduz Mehmet
岡山大学大学院医歯学総合研究科病態機構学講座:口腔病理病態学分野
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Katase Naoki
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry And Pharmaceutical S
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Tujigiwa Hidetugu
Department Of Oral Pathology And Medicine Graduate School Of Medicine And Dentistry. Okayama Univers
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Tujigiwa Hidetugu
Dept. Of Oral Pathology Okayama Univ. Dental School.
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Siar Chong
Department Of Oral Pathology Oral Medicine & Periodontology Faculty Of Dentistry University Of M
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Kawakami Toshiyuki
Hard Tissue Pathology Matsumoto Dental University Institute For Dental Science
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Nakano Keisuke
Department Of Oral Pathology And Medicine Graduate School Of Medicine Dentistry And Pharmaceutical S
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Tsujigiwa Hidetsugu
Department Of Oral Pathology School Of Dentistry Okayama University
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Siar Chong
Department Of Oral Pathology Oral Medicine & Periodontology Faculty Of Dentistry University Of M
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