Comparison of Bone Mineral Density and Area of Newly Formed Bone Around Ti-15%Zr-4%Nb-4%Ta Alloy and Ti-6%Al-4%V Alloy Implants
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概要
- 論文の詳細を見る
A newly developed titanium alloy, Ti-15%Zr-4%Nb-4%Ta (Ti15Zr4Nb4Ta), has been shown to have excellent mechanical characteristics, corrosion fatigue strength, anticorrosion, cytocompatibility, and biocompatibility. The purpose of this study was to compare the bone mineral density (BMD) and area of newly formed bone around Ti15Zr4Nb4Ta implants to that around Ti-6%Al-4%V alloy (Ti6Al4V) implants. We inserted 2 types of implants (surface treat of the machine and the blast implant) in New Zealand white rabbit femurs under general anesthesia. The rabbit was done perfusion fixation of 4, 8, 16, 24, and 48 weeks later, and the femurs with the implants were collected and we observed the surrounding bone by an implant drawing test. We measured the BMD and the area of the newly formed bone surrounding the implant inserted part using image analysis software Image-Pro PLUS Ver. 4.0^[○!R] which it developed newly in micro focus computed tomography (micro CT). The results showed the machine and the blast implant together, which the BMD and area around the Ti15Zr4Nb4Ta implants were comparable to or greater than those around the Ti6Al4V implants. These results suggested that the new alloy, Ti15Zr4Nb4Ta, might be useful for orthopedic or dental implants with the added advantage of superior biologic safety and mechanical properties than the current alloy, Ti6Al4V.
- 硬組織再生生物学会の論文
著者
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Tamaki Hiroyuki
Department Of Physiological Sciences National Institute Of Fitness And Sports
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Tamaki Hiroyuki
Department Of Cardiology Mimihara General Hospital
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Nakada Hiroshi
Department of Biotechnology, Faculty of Engineering, Kyoto Sangyo University
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LEGEROS Racquel
ニューヨーク大学
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Nakada Hiroshi
Department Of Gnatho-oral Prosthetic Rehabilitation Nihon University School Of Dentistry At Matsudo
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Sakae Toshiro
Department of Anatomy, Nihon University School of Dentistry at Matsudo
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Sakae Toshiro
日本大学松戸歯学部 組織発生解剖学
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Sakai Takeshi
Inst. Of Mineralogy Petrology And Economic Geology Graduate School Of Sci. Tohoku Univ.
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Sakae Toshiro
Department Of Anatomy Nihon University School Of Dentistry At Matsudo
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Ookubo Atsushi
Department Of Histology Cytology And Developmental Anatomy Nihon University School Of Dentistry At M
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Legeros Racquel
Department Of Biomaterials And Biomimetics New York University College Of Dentistry
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Legeros Racquel
Department Of Biomaterials And Biomimetics College Of Dentistry New York University
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Legeros Racquel
日本大学松戸歯学部 組織・発生・解剖学講座
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Tanimoto Yasuhiro
Departments of Dental Biomaterials, Nihon University School of Dentistry at Matsudo
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Nakada Hiroshi
Department Of Biotechnology Faculty Of Engineering Kyoto Sangyo University
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Sakae Toshiro
Department Of Anatomy Ii Nihon University School Of Dentistry At Matsudo
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Numata Yasuko
Nihon University Graduate School Of Dentistry At Matsudo Complete Denture Prosthodontics
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Kato Takao
Department Of Oral And Maxillofacial Implantology Nihon University School Of Dentistry At Matsudo
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Tamaki Hiroyuki
Department Of Oral And Maxillofacial Implantology Nihon University School Of Dentistry At Matsudo
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Okazaki Yoshimitsu
Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Sc
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Katou Takao
Department of Oral and Maxillofacial Implantology, Nihon University School of Dentistry at Matsudo
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Kobayashi Kihei
Nihon University Research Center
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Kuwada Takao
Lebra Laboratory For Electron Beam Research And Application Institute Of Quantum Science Nihon Unive
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Tanaka Shigeo
Department Of Anatomy Nihon University School Of Dentistry At Matsudo
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Sakai Takeshi
Nihon Univ. Tokyo Jpn
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Tanimoto Yasuhiro
Department Of Dental Biomaterials Nihon University School Of Dentistry At Matsudo
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Sakae Toshiro
Departments Of Oral Histology Nihon University School Of Dentistry
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Nakada Hiroshi
Graduate School Of Science And Technology Nihon University
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Okazaki Yoshimitsu
Institute For Human Science And Biomedical Engineering National Institute Of Advanced Industrial Sci
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Kobayashi Kihei
Nihon University Of Dentistry At Matsudo
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Kuwada Takao
Lebra Laboratory For Electron Beam Research And Application Institute Of Quantum Science Nihon Unive
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Katou Takao
Department of Applied Chemistry, Faculty of Engineering, Yamagata University
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