抗生物質の食糧工業への應用に關する研究(第1報) : 數種抗生物質の牛乳に對する應用(その1)

概要

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We have studied to find some method appliable to the preservation of cow's milk. We isolated 17 strains of putrefactive bacteria from market milk (raw, condensed, and powdered milk) and butter, and examined their characters.We prepared cow's milk medium in test tubes; penicillin, streptomycin, chloromycetin, patulin, aureomycin or terramycin was added to it at the concentrations of 1/10,000,1/50,000,1/200,000,and then the milk bacteria were inoculated separately, in order to observe their behaviour in the presence of the antibiotics.At the same time with observation on the appearance of growth, the analysis was made with respect to increase of acidity, presence of peptonizing effect, production of ammonia and indol, foul odour, colourization effect etc.As the result, chloromycetin, aureomycin and terramycin are effective against acid-production and coagulation, and high concentrated chloromycetin and aureomycin can prevent the putrefaction which follows casein decomposition.
社団法人日本生物工学会の論文
1952-07-15