Effect of chondroitin sulfate and hyaluronic acid on gene expression in a three-dimensional culture of chondrocytes

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概要

• 論文の詳細を見る

• The effect of glycosaminoglycan addition on a three-dimensional (3D) culture of porcine chondrocyte cells was investigated with a view to use in cartilage regenerative medicine. Chondroitin sulfate C increased the mRNA expression of type 2 collagen, while chondroitin sulfate A did not. Hyaluronic acid of high molecular weight markedly decreased the mRNA expression of both aggrecan and type 2 collagen, although hyaluronic acid of low molecular weight showed no apparent effect.

• 社団法人日本生物工学会の論文
• 2005-07-25

著者

• TAKAGI Mutsumi

  International Center for Biotechnology, Osaka University

• YOSHIDA Toshiomi

  International Center for Biotechnology, Osaka University

• Yoshida Toshiomi

  大阪大学生物工学国際交流センター

• Yoshida Toshiomi

  International Center Of Cooperative Research In Biotechnology Faculty Of Engineering Osaka Universit

• Yoshida T

  International Center For Biotechnology Osaka University

• Yoshida Toshiomi

  International Center For Biotechnology Osaka University

• 吉田 豊和

  岐阜大・工・生命工

• Takagi Mutsumi

  International Center For Biotechnology Osaka University:(present Address)division Of Biotechnology A

• Takagi M

  International Center For Biotechnology Osaka University

• Takagi M

  Japan Advanced Inst. Of Sci. And Technol. Ishikawa Jpn

• Takagi M

  Osaka Univ. Osaka Jpn

• Wakitani Shigeyuki

  Orthopedic Surgery Osaka City Univ. School Of Medicine 1-4-3 Asahi-machi Abeno-ku Osaka Osaka 545-85

• Nishimoto Shohei

  International Center for Biotechnology, Osaka University

• Nihira Takuya

  International Center for Biotechnology, Osaka University

• Yoshida T

  Division Of Material And Biological Graduate School Japan Women's University

• Nihira Takuya

  International Center For Biotechnology Osaka University

• Yoshida Toshiomi

  International Center For Biotechology Osaka University

• Yoshida T

  Kinki Univ. Nara Jpn

• Yoshida Toyokazu

  Dept. Food Nutri. Fac. Agr. Kinki Univ.

• Takagi Mutsumi

  Internatioal Center For Biotechnology Osaka University

• Nishimoto Shohei

  International Center For Biotechnology Osaka University

• Yoshida Toshiomi

  Osaka Univ. Osaka Jpn

• Yoshida Takao

  Institute For Biomolecular Science Faculty Of Science Gakushuin University

• Nihira Takuya

  International Center For Biotechnology Osaka Univ.

• Yoshida Toshiomi

  Internatioal Center For Biotechnology Osaka University

• 吉田 豊和

  岐阜大 工

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