還元麦芽水飴「マルチ」のラットに対する長期投与の影響特に腫瘍発生について

概要

論文の詳細を見る
"Malti" is a commercial sweet material which contains maltitol in a concentration of more than 75 per cent. Groups of male and female Wistar rats were maintained on diets containing "Malti" in concentrations of 3% and 10% for one and a half years (78 weeks), in order to study long-term toxicity with special reference to carcinogenicity. During the experiment, no unusual signs were observed among the test rats. Growth and food consumption data revealed no Malti-related differences. Hematologic parameters and clinical blood chemistry data showed no significant differences except for a lowering of serum cholesterol level in all Malti groups. Pathologic and patho-histologic examinations revealed no diffinite abnormalities. Carcinogenit activity was also negative.
日本トキシコロジー学会の論文
1977-10-15