Possible Mechanism of Hypoglycemic Effect of 4-Hydroxybenzoic Acid, a Constituent of Pandanus odorus Root
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概要
- 論文の詳細を見る
We studied the hypoglycemic effect of 4-hydroxybenzoic acid, a constituent of the root of Pandanus odorus Ridl. (Pandanaceae, Thai name: Toei-hom), in streptozotocin-diabetic rats. Oral administration of 4-hydroxybenzoic acid caused a decrease in plasma glucose levels dose-dependently in the diabetic rat. The constituent did not affect serum insulin level and liver glycogen content in the diabetic model, but increased glucose consumption in normal and diabetic rat diaphragms. These results suggest that 4-hydroxybenzoic acid produces a hypoglycemic effect mediated by an increase in the peripheral glucose consumption.
- 社団法人 日本薬理学会の論文
- 1998-11-01
著者
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Watanabe Hiroshi
Department of Cardiology, Niigata City General Hospital
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Watanabe H
Toyama Medical And Pharmaceutical Univ. Toyama Jpn
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PEUNGVICHA Penchom
Departmen t of Physiology, Faculty of Pharmacy, Mahidol University
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THIRAWARAPAN Suwan
Departmen t of Physiology, Faculty of Pharmacy, Mahidol University
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Thirawarapan Suwan
Departmen T Of Physiology Faculty Of Pharmacy Mahidol University
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Peungvicha Penchom
Departmen T Of Physiology Faculty Of Pharmacy Mahidol University
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Watanabe Hiroshi
Department Of Applied Chemistry And Bioengineering Graduate School Of Engineering Osaka City Univers
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