1-アシル-1-チオカルボカチオンを用いる合成反応
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The carbon-carbon bond forming reactions of 1-acyl-1-thiocarbocations are described. The cations can easily be generated from α-acyl-α-chlorosulfides under the Friedel-Crafts reaction conditions or from α-acylsulfoxides under the Pummerer reaction conditions. The reactions are classified into the following four features : 1) electrophilic aromatic substitution, 2) ene reaction, 3) olefin cyclization, and 4) cationic polar cycloaddition. Applications of these reactions to synthe-ses of some medicines and natural products are also mentioned.
- 有機合成化学協会の論文
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