Chemistry of O-Silylated Ketene Acetals. Novel Chemical Transformation of Vinyl Sulfoxides and Related Sulfoxides(Organic,Chemical)

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概要

• 論文の詳細を見る

• It is shown that vinyl sulfoxides undergo two novel modes of reactions induced selectively by the O-silylated ketene acetal used. Vinyl sulfoxides, on treatment with bulky tert-butyldimethylsilyl ketene acetals, undergo a Michael-Pummerer-type reaction to give γ-siloxy-γ-(phenylthio)esters, while with less bulky trimethylsilyl ketene acetals they undergo a double carbon-carbon bond-forming reaction to give 3-(phenylthio)adipates. The reaction of related sulfoxides with O-silylated ketene acetals was also examined.

• 社団法人日本薬学会の論文
• 1987-02-25

著者

• 田村 恭光

  Faculty Of Pharmaceutical Sciences Osaka University

• 北 泰行

  Faculty of Pharmaceutical Sciences, Osaka University

• 北 泰行

  大阪大学大学院薬学研究科

• 安田 均

  Faculty Of Pharmaceutical Sciences Osaka University

• Kita Yasuyuki

  Graduate School Of Pharmaceutical Sciences Osaka University Yamadaoka

• 田村 修

  Faculty of Pharmaceutical Sciences, Osaka University

• 三木 隆

  Faculty Of Pharmaceutical Sciences Osaka University

• 伊藤 文雄

  Pharmaceutical Research Laboratories Iii Takeda Chemical Industries Ltd.

• 伊藤 文雄

  Faculty of Pharmaceutical Sciences, Osaka University

• 田村 修

  Faculty Of Pharmaceutical Sciences Osaka University

• 田村 修

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 北 泰行

  Faculty Of Pharmaceutical Sciences Osaka University

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