Syntheses of Arylacetone and Arylacetonitrile by Friedel-Crafts Reaction with α-Chloro-α-(methylthio)-substituted Acetone and Acetonitrile
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概要
- 論文の詳細を見る
Novel preparative methods for arylacetone and arylacetonitrile are described. Friedel-Crafts reactions of aromatic compounds with α-chloro-α-(methylthio) acetone (4) and α-chloro-α-(methylthio) acetonitrile (7) in the presence of Lewis acid afforded α-(methylthio)-arylacetone (5) and α-(methylthio) arylacetonitrile (8), respectively. Compounds (5) and (8) were converted into the corresponding arylacetone (6) and arylacetonitrile (9) by reduction with zinc dust in acetic acid.
- 社団法人日本薬学会の論文
- 1982-10-25
著者
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田村 恭光
Faculty Of Pharmaceutical Sciences Osaka University
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石橋 弘行
Faculty of Pharmaceutical Sciences, Osaka University
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崔 洪大
Faculty of Pharmaceutical Sciences, Osaka University
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上田 祐子
Faculty Of Pharmaceutical Sciences Osaka University
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水谷 昌子
Faculty of Pharmaceutical Sciences, Osaka University
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石橋 弘行
金沢大学薬学部
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石橋 弘行
京都薬科大学
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崔 洪大
Faculty Of Pharmaceutical Sciences Osaka University
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水谷 昌子
Faculty Of Pharmaceutical Sciences Osaka University
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