Pummerer-Type Reaction of α-Acylsulfides Using Phenyl Iodosyl Bis(trifluoroacetate)
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概要
- 論文の詳細を見る
Treatment of α-acylsulfides with phenyl iodosyl bis(trifluoroacetate) (PIFA) resulted in a Pummerer-type reaction to give the same products as obtained by the Pummerer reaction of the α-acylsulfoxides. The Pummerer-type reaction of α-acylsulfides using PIFA was applied to Friedel-Crafts type cyclization of N-phenyl-α-(methylthio)acetanilide (1) and ethyl α-(1-phenethylthio)-acetate (9) to give N-phenyl-3-(methylthio)oxindole (3) and ethyl isothiochroman-1-carboxylate (10), respectively, olefin cyclization of α-(methylthio)acetamides (11,13 and 15) to give the lactams (12,14 and 16), and also intermolecular condensation and α-methoxylation of methyl α-(methylthio)acetate (7).
- 社団法人日本薬学会の論文
- 1986-03-25
著者
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田村 恭光
Faculty Of Pharmaceutical Sciences Osaka University
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春田 純一
Faculty Of Pharmaceutical Sciences Osaka University
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矢倉 隆之
Faculty of Pharmaceutical Sciences, Osaka University
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城内 善昭
Faculty of Pharmaceutical Sciences, Osaka University
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城内 善昭
Faculty Of Pharmaceutical Sciences Osaka University
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矢倉 隆之
Kyoto Pharmaceutical University
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