Synthesis and Thermolysis of 3-Azidoindolenines

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概要

• 論文の詳細を見る

• Several new 3-azidoindolenines have been synthesized in high yields (i) by the reaction of 2,3-disubstituted indoles with iodine azide or bromine azide, and (ii) by the reaction of 3-chloroindolenines with sodium azide in acetic acid. The 3-azidoindolenines undergo thermal rearrangement in variable yields and ratios to quinoxalines and quinazolines, along with the formation of the parent indoles. The ring-expansion of 3-azido-2,3-diphenylindolenine to 2,3-diphenylquinoxaline also occurs on treatment with acid but in much lower yield. Photolysis of the 3-azidoindolenines gives the parent indoles as major products.

• 社団法人日本薬学会の論文
• 1978-09-25

著者

• 田村 恭光

  Faculty Of Pharmaceutical Sciences Osaka University

• 千 文宇

  Faculty of Pharmaceutical Sciences, Osaka University

• 権 順度

  Faculty of Pharmaceutical Sciences, Osaka University

• 池田 正澄

  Faculty of Pharmaceutical Sciences, Osaka University

• 権 順度

  Faculty Of Pharmaceutical Sciences Osaka University

• 池田 正澄

  Kyoto Pharmaceutical University

• 千 文宇

  Faculty Of Pharmaceutical Sciences Osaka University

• 西田 裕

  Faculty of Pharmaceutical Sciences, Osaka University

• 西田 裕

  Nippon Shinyaku Company Ltd.

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