Neutropenia Associated with Osteomyelitis due to Hepatozoon canis Infection in a Dog
スポンサーリンク
概要
- 論文の詳細を見る
A 4-year-old, intact male Shiba dog was referred to Yamaguchi University Animal Medical Center, Yamaguchi, Japan for the following complaints: anorexia, lethargy, intermittent fever, gingival bleeding, and abdominal purpura. The dog presented with persistent neutropenia. Histopathological examination of the bone marrow sample revealed round to oval structures that resembled Hepatozoon micromerozoites and formed a "wheel-spoke" pattern. Furthermore, mature neutrophils were observed around these structures. PCR and sequencing using bone marrow aspirate confirmed Hepatozoon canis (H. canis) infection. These findings suggest that neutropenia observed in this case was associated with osteomyelitis due to H. canis infection. This is the first report of neutropenia associated with H. canis infection. H. canis infection can be included in the differential diagnosis in canine cases of neutropenia in areas where the disease is endemic.
著者
-
SHIMOKAWA MIYAMA
Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Agricultur
-
HIRAOKA Hiroko
Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Agricultur
-
BABA Kenji
Laboratory of Veterinary Parasitology, Department of Veterinary Medicine, Faculty of Agriculture, Ya
-
OKUDA Masaru
Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Agricultur
-
MIZUNO Takuya
Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Agricultur
-
Baba Kenji
Department Of Veterinary Internal Medicine Graduate School Of Agricultural And Life Sciences The Uni
-
Hisasue Masaharu
Laboratory Of Internal Medicine Ii School Of Veterinary Medicine Azabu University
-
Endo Yasuyuki
Laboratory Animal Research Center The Institute Of Medical Science The University Of Tokyo
-
UMEKI Saori
Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Agricultur
-
Inokuma Hisashi
Department Of Applied Veterinary Medicine Obihiro University Of Agriculture And Veterinary Medicine
-
SADA Kumiko
Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Agricultur
関連論文
- An Updated Nation-Wide Epidemiological Survey of Feline Immunodeficiency Virus (FIV) Infection in Japan
- Preparation of Positive Control Platelets for Detection of Canine Platelet Surface-Associated IgG, IgM and Complement (C3) by Flow Cytometry
- Prekallikrein Deficiency in a Dog
- Characterization of Monocyte-Derived Dendritic Cells from Cats Infected with Feline Immunodeficiency Virus
- Detection of Antibodies against Japanese Encephalitis Virus in Raccoons, Raccoon Dogs and Wild Boars in Japan
- Bone Marrow Colony-Forming Unit Assay in Cats With Naturally Occurring Myelodysplastic Syndromes
- Differential Diagnosis of Feline Leukemia Virus Subgroups Using Pseudotype Viruses Expressing Green Fluorescent Protein
- Application of Polymerase Chain Reaction to Analysis of Antigen Receptor Rearrangements to Support Endoscopic Diagnosis of Canine Alimentary Lymphoma
- A Mechanism of Excessive Accumulation of Abomasal Gas in Vagotomized Cattle Determined Using Fluoroscopy
- Aberrations of the FHIT Gene and Fhit Protein in Canine Lymphoma Cell Lines
- Molecular Cloning of the Canine Fragile Histidine Triad (FHIT) Gene and Fhit Protein Expression in Canine Peripheral Blood Mononuclear Cells
- Inhibitory Effect of Newly Developed CXC-Chemokine Receptor 4 Antagonists on the Infection with Feline Immunodeficiency Virus(Virology)
- Inhibition of the Replication of Feline Immunodeficiency Virus by Lentiviral Vector-Mediated RNA Interference in Feline Cell Lines(Clinical Pathology)
- Comparison of PSP Amino Acid Sequences between Domestic Animals
- Use of Formalin-Fixed Paraffin-Embedded Tissue and Single-Strand Conformation Polymorphism Analysis for Polymerase Chain Reaction of Antigen Receptor Rearrangements in Dogs
- Cutaneous Nocardiosis in a Cat
- Purulent Necrotic Dislocation of the Hip Joint Associated with Umbilical Infection in a Foal
- Temporal Changes in Concentrations of Branched-Chain Amino Acids in Plasma on Healthy Mares and Foals from Birth to 24 Weeks of Age
- A Case Report: a Dog with Acute Onset of Hepatozoon canis Infection
- Genotypic Diversity of Theileria orientalis Detected from Cattle Grazing in Kumamoto and Okinawa Prefectures of Japan
- Epidemiological Survey of Theileria orientalis Infection in Grazing Cattle in the Eastern Part of Hokkaido, Japan
- Pharmacokinetics of the Gastroprokinetic Agent Mosapride Citrate after Single Oral Administration in Horses
- MDCT Images of the Head of a Horse with Malignant Melanoma
- Evaluation of the Hemodynamic Impact of Continuous Renal Replacement Therapy in Healthy Dogs
- Nafamostat Mesilate Is Not Appropriate as an Anticoagulant during Continuous Renal Replacement Therapy in Dogs
- Comparison of Two Hemoplasma Species on Hematological Parameters in Cattle
- A Case of Atypical Canine Lymphoma with Oral Mass and Multiple Osteolysis
- Neutropenia Associated with Osteomyelitis due to Hepatozoon canis Infection in a Dog
- A Case of Iriomote Cat (Prionailurus bengalensis iriomotensis) with Hepatozoon felis Parasitemia
- Crossreactivity of Antibodies to Canine CD25 and Foxp3 and Identification of Canine CD4+CD25 +Foxp3+ Cells in Canine Peripheral Blood
- Magnetic Resonance Imaging and Clinical Findings in a Miniature Schnauzer with Hypodipsic Hypernatremia
- Molecular Epidemiological Survey of Theileria orientalis in Thua Thien Hue Province, Vietnam
- An Epidemiological Survey of Feline Hemoplasma Infection in Japan
- Aggregability and Post-Transfusion Survival of Canine Platelets in Stored Whole Blood
- The Prokinetic Effect of Mosapride Citrate on Horse Gastric Emptying Rates
- Focus Assay on RD114 Virus in QN10S Cells(Virology)
- Successful Treatment of Bacillary Hemoglobinuria in Japanese Black Cows
- Slow Recovery of Blood Glucose in Insulin Tolerance Test during the Prepartum Transition Period Negatively Impacts the Nutritional Status and Reproductive Performance Postpartum of Dairy Cows
- Detection of the New Ehrlichia Species Closely Related to Ehrlichia ewingii from Haemaphysalis longicornis in Yonaguni Island, Okinawa, Japan
- Nationwide Survey of Leptospira Antibodies in Dogs in Japan: Results from Microscopic Agglutination Test and Enzyme-Linked Immunosorbent Assay
- A Dog with Myelodysplastic Syndrome: Chronic Myelomonocytic Leukemia
- Prevalence of Canine Distemper Virus, Feline Immunodeficiency Virus and Feline Leukemia Virus in Captive African Lions (Panthera leo) in Japan
- Detection of Rickettsia tamurae DNA in Ticks and Wild Boar (Sus scrofa leucomystax) Skins in Shimane Prefecture, Japan
- Development of High-Grade B-Cell Lymphoma Concurrent with T-Cell Chronic Lymphocytic Leukemia in a Dog
- An Epidemiological Survey of Hemoplasma Infection in Iriomote Cats (Prionailurus bengalensis iriomotensis)
- A PCR Based Survey of Babesia ovata in Cattle from Various Asian, African, and South American Countries
- Abnormal Erythroid Cell Proliferation and Myelofibrosis in a Cat
- Dual Presence of Anaplasma phagocytophilum and Its Closely Related Anaplasma sp. in Ixodid Ticks in Hokkaido, Japan, and Their Specific Molecular Detection
- Prevalence and Risk Factor Analysis of Bovine Hemoplasma Infection by Direct PCR in Eastern Hokkaido, Japan
- Overexpression of Interleukin 2 Receptor, Thymidine Kinase and Immunoglobulin-Associated Alpha-1 Messenger RNA in a Clinical Case of Enzootic Bovine Leukosis
- Calf Form Bovine Leukosis with Lameness in a Holstein Heifer
- Thymic Lymphosarcoma with Brain Involvement in a Holstein Heifer
- Establishment of Five Canine Lymphoma Cell Lines and Tumor Formation in a Xenotransplantation Model
- Molecular Epidemiological Survey of the Babesia gibsoni cytochrome b Gene in Western Japan
- A Clinical Case of Severe Anemia in a Sheep Coinfected with Mycoplasma ovis and Candidatus Mycoplasma haemovis' in Hokkaido, Japan
- Accumulation of Xenotransplanted Canine Bone Marrow Cells in NOD/SCID/γcnull Mice with Acute Hepatitis Induced by CCl4
- Astasia and Pyrexia Related to Borrelia garinii Infection in Two Dogs in Hokkaido, Japan
- Identification of Cell Surface Antigen Expression in Canine Hepatocellular Carcinoma Cell Lines
- Effect of Chronic Hemoplasma Infection on Cattle Productivity
- Specific Molecular Detection and Characterization of Anaplasma marginale in Mongolian Cattle
- Generalized Alopecia with Vasculitis-Like Changes in a Dog with Babesiosis
- Utility of Serum Thymidine Kinase Activity Measurements for Cases of Bovine Leukosis with Difficult Clinical Diagnoses
- Epidemiological Survey of Tick-Borne Protozoal Infection in Iriomote Cats and Tsushima Leopard Cats in Japan
- Molecular Cloning of Canine nm23 cDNAs and Their Expression in Normal and Tumor Tissues
- Prevalence and Molecular Analyses of Hemotrophic Mycoplasma spp. (Hemoplasmas) Detected in Sika Deer (Cervus nippon yesoensis) in Japan
- Notch2 Transduction by Feline Leukemia Virus in a Naturally Infected Cat