Abnormal Erythroid Cell Proliferation and Myelofibrosis in a Cat
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概要
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A cat was presented with severe progressive anemia despite marked erythroblastosis. The cat was negative for feline leukemia virus antigen and feline immunodeficiency virus antibody. Bone marrow cytology revealed an excess of erythroid cells with a predominance of prorubricytes and basophilic rubricytes. No response to immunosuppressive therapy was obtained, and a tentative diagnosis of myelodysplastic syndrome was made. The cat showed a partial response to low-dose cytarabine (20 mg/m2 subcutaneously q24) but died 51 days after the 1st admission. Histopathological examination revealed fibrosis in the bone marrow and marked infiltration of erythroid cells into other organs.
著者
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MIURA Naoki
Laboratory of Veterinary Surgery, Department of Veterinary Medicine, Faculty of Agriculture, Kagoshi
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Endo Yasuyuki
Laboratory Animal Research Center The Institute Of Medical Science The University Of Tokyo
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MIYOSHI Noriaki
Laboratory of Pathology, Department of Veterinary Medicine, Kagoshima University
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Miyoshi Noriaki
Dep. Of Veterinary Histopathology Joint Fac. Of Veterinary Medicine Kagoshima Univ.
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MIYOSHI Noriaki
Laboratory of Veterinary Histopathology, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, 1–21–24 Korimoto, Kagoshima 890–0065, Japan
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IWANAGA Tomoko
Laboratory of Veterinary Diagnostic Imaging, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, 1–21–24 Korimoto, Kagoshima 890–0065, Japan
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MOMOI Yasuyuki
Laboratory of Diagnostic Imaging, Joint Faculty of Veterinary Medicine, Kagoshima University, 1–21–24 Korimoto, Kagoshima 890–0065, Japan
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MOMOI Yasuyuki
Laboratory of Veterinary Diagnostic Imaging, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, 1–21–24 Korimoto, Kagoshima 890–0065, Japan
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ENDO Yasuyuki
Laboratory of Small Animal Internal Medicine, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, 1–21–24 Korimoto, Kagoshima 890–0065, Japan
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MIURA Naoki
Laboratory of Veterinary Diagnostic Imaging, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, 1–21–24 Korimoto, Kagoshima 890–0065, Japan
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MIYOSHI Noriaki
Laboratory of Histopathology, Joint Faculty of Veterinary Medicine, Kagoshima University
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MOMOI Yasuyuki
Laboratory of Diagnostic Imaging, Department of Veterinary Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, 1–21–24 Kohrimoto, Kagoshima 890–0065, Japan
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