Molecular Epidemiological Survey of the Babesia gibsoni cytochrome b Gene in Western Japan
スポンサーリンク
概要
- 論文の詳細を見る
In this study, we conducted a survey of the cytochrome b (cytb) gene of Babesia gibsoni (B. gibsoni) isolated from clinical cases to determine the prevalence of potential atovaquone (ATV)-resistant variants. Ninety-two blood samples were collected from naturally B. gibsoni infected dogs. The cytb nucleotide sequence was determined by direct sequencing. Twelve non-synonymous amino acid substitutions were identified in cytb. The principal ATV-resistant substitution, M121I, was detected in three cases. This survey determined that potentially ATV-resistant B. gibsoni strains are present in dogs in Japan.
- 日本獣医学会の論文
著者
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SAKUMA Masato
Laboratory of Veterinary Internal Medicine, Faculty of Agriculture, Kagoshima University
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Endo Yasuyuki
Laboratory Animal Research Center The Institute Of Medical Science The University Of Tokyo
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SETOGUCHI Asuka
Laboratory of Small Animal Internal Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University
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FUKUDA Kenta
ADTEC Co., Ltd.
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TAKAYAMA Katsuyoshi
ADTEC Co., Ltd.
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KOBAYASHI Yukuharu
ADTEC Co., Ltd.
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MIYAMA Takako
Veterinary Teaching Hospital, Kagoshima University
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ENDO Yasuyuki
Laboratory of Small Animal Internal Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University
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SAKUMA Masato
Laboratory of Small Animal Internal Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University
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