A Novel Pair of Terminal Protein and Telomere-Associated Protein for Replication of the Linear Chromosome of Streptomyces griseus IFO13350
スポンサーリンク
概要
- 論文の詳細を見る
The linear chromosome of Streptomyces griseus IFO13350 contains not only atypical telomere sequences but also probable pseudogenes for two typical telomeric proteins. Two identical operons (SGR98t-SGR97t near one telomere and SGR7041t-SGR7042t near the other telomere) in the terminal inverted repeat sequence were predicted to encode a novel pair of telomeric proteins. SGR97t, a 185-amino-acid protein showing only 18% amino acid sequence identity to typical terminal proteins of Streptomyces, was found to be attached to the chromosomal ends, as determined by immunological analysis. On the other hand, electrophoretic mobility shift assays showed that SGR98t, an 837-amino-acid protein having a DnaB-like helicase C-terminal domain, was capable of binding specifically to the single-stranded terminal DNA corresponding to the 3′ overhang of the replication intermediate. These results indicate that SGR97t (and SGR7042t) and SGR98t (and SGR7041t) were the functional telomeric proteins in the replication of the linear chromosome of S. griseus IFO13350.
- 社団法人 日本農芸化学会の論文
著者
-
HORINOUCHI Sueharu
Department of Biotechnology, University of Tokyo
-
SUZUKI Hirokazu
Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Hokuriku University
-
OHNISHI Yasuo
Department of Biotechnology, Graduate School of Agriculture and Life Sciences, The University of Tok
-
MARUSHIMA Kazuya
Department of Biotechnology, Graduate School of Agriculture and Life Sciences, The University of Tok
関連論文
- Transglycosylation Activity of Dictyoglomus thermophilum Amylase A
- Effects of 1-Benzylxanthines on Cyclic AMP Phosphodiesterase 4 Isoenzyme(Medicinal Chemistry)
- Cyclic AMP Phosphodiesterase 4 Isoenzyme Inhibitory Activity of (R)- and (S)-Isomer of 7-Methyl- or 8-Alkyl-4, 5, 7, 8-tetrahydroimidazo [2,1-i] -purin-5-one (Highlihted paper slected by Editor-in-chief)(Medicinal Chemistry)
- Synthesis and Cyclic AMP Phosphodiesterase 4 Isoenzyme Inhibitory Activity of Heterocycle Condensed Purines
- Phosphodiesterase 4 Isoenzyme Inhibitory Activity of 3-Phenylxanthines and 4-Phenyl[i]condensed-purines
- Condensed-Purines Syntheses of Tetrahydro-1,4-diazepino[1,2,3-gh]purin-2-one and Hexahydro-1,4-diazocino[1,2,3-gh]purin-2-one
- Anthocyanin acyltransferase engineered for the synthesis of a novel polyacylated anthocyanin
- Identification of a cDNA Encoding Malonyl-Coenzyme A: Anthocyanidin 3-O-Glucoside 6"-O- Malonyltransferase from Cineraria (Senecio cruentus) Flowers
- Structure-activity Relationship for FR901464 : A Versatile Method for the Conversion and Preparation of Biologically Active Biotinylated Probes
- Short-step Syntheses of All Stereoisomers of Preussin and Their Bioactivities(Organic Chemistry)
- Radicicol Binding to Swo1/Hsp90 and Inhibition of Growth of Specific Temperature-sensitive Cell Cycle Mutants of Fission Yeast(Biochemistry & Molecular Biology)
- Mechanism of Cell Cycle Arrest Caused by Histone Deacetylase Inhibitors in Human Carcinoma Cells
- Identification of Radicicol as an Inhibitor of In Vivo Ras/Raf Interaction with the Yeast Two-hybrid Screening System
- Identification of Preussin as a Selective Inhibitor for Cell Growth of the Fission Yeast ts Mutants Defective in Cdc2-Regulatory Genes
- Morphology of Ras- Transformed Cells Becomes Apparently Normal Again with Tyrosine Kinase Inhibitors without a Decrease in the Ras- GTP Complex^1
- Phosphatidylinositol-3 Kinase in Fission Yeast : A Possible Role in Stress Responses
- Basidifferquinone Analogues, Basidifferquinone B and C, Which Induce Fruiting-body Formation of a Basidiomycete, Favolus arcularius
- Radicicol, an Agent Inducing the Reversal of Transformed Phenotypes of src-Transformed Fibroblasts
- Basidifferquinone, a New Inducer for Fruiting-body Formation of a Basidiomycetes Favolus arcularius from a Streptomyces Strain II. Structure of Basidifferquinone(Organic Chemistry)
- Basidifferquinone, a New Inducer for Fruiting-body Formation of a Basidiomycetes Favolus arcularius from a Streptomyces Strain I. Screening and Isolation(Organic Chemistry)
- Oxygenation Reactions of Various Tricyclic Fused Aromatic Compounds Using Escherichia coli and Streptomyces lividans Transformants Carrying Several Arene Dioxygenase Genes(Microbiology & Fermentation Technology)
- Neuritogenic Activities of 1-Alkyloxygenipins
- Characteristic Properties of Genipin as an Activator in Neuronal Nitric Oxide Synthase
- Biotransformation of Phenanthrene and 1-Methoxynaphthalene with Streptomyces lividans Cells Expressing a Marine Bacterial Phenanthrene Dioxygenase Gene Cluster(Microbiology & Fermentation Technology)
- Addition of a Small Amount of an Endoglucanase Enhances Cellulose Production by A cetobacter xylinum
- GEX1 Compounds, Novel Antitumor Antibiotics Related to Herboxidiene, Produced by Streptomyces sp. : II. The Effects on Cell Cycle Progression and Gene Expression
- A Novel Pair of Terminal Protein and Telomere-Associated Protein for Replication of the Linear Chromosome of Streptomyces griseus IFO13350
- GriC and GriD Constitute a Carboxylic Acid Reductase Involved in Grixazone Biosynthesis in Streptomyces griseus
- Conversion of a Cyanhydrin Compound into S-(-)-3-Phenyllactic Acid by Enantioselective Hydrolytic Activity of Pseudomonas sp. BC-18
- Nitrile Hydratase Gene from Rhodococcus sp. N-774 Requirement for Its Downstream Region for Efficient Expression
- Induction of a Ribotoxic Stress Response That Stimulates Stress-Activated Protein Kinases by 13-Deoxytedanolide, an Antitumor Marine Macrolide
- Identification of the Cellulose-Binding Domain of a Bacillus subtilis Endoglucanase Distinct from Its Catalytic Domain
- Characterization of the Leader Peptide of an Endo-type Cellulase Produced by an Alkalophilic Streptomyces Strain(Microbiology & Fermentation Industry)
- Chitinase Inhibitor Allosamidin Is a Signal Molecule for Chitinase Production in Its Producing Streptomyces : II. Mechanism for Regulation of Chitinase Production by Allosamidin through a Two-component Regulatory System
- Structures of Grixazone A and B, A-Factor-dependent Yellow Pigments Produced under Phosphate Depletion by Streptomyces griseus
- Increased Cellulose Production from Sucrose with Reduced Levan Accumulation by an Acetobacter Strain Harboring a Recombinant Plasmid
- Purification and Properties of Thermostable β-Tyrosinase from an Obligately Symbiotic Thermophile, Symbiobacterium thermophilum
- Purification and Properties of Thermostable Tryptophanase from an Obligately Symbiotic Thermophile, Symbiobacterium thermophilum(Microbiology & Fermentation Industry)
- Replacements of Amino Acid Residues at Subsites and Their Effects on the Catalytic Properties of Rhizomucor pusillus Pepsin, an Aspartic Proteinase from Rhizomucor pusillus
- Site-Directed Mutagenesis of Conserved Trp39 in Rhizomucor pusillus Pepsin: Possible Role of Trp39 in Maintaining Tyr75 in the Correct Orientation for Maximizing Catalytic Activity
- Involvement of AfsA in A-factor Biosynthesis as a Key Enzyme
- Self-activation of Serine/Threonine Kinase AfsK on Autophosphorylation at Threonine-168
- AdpA, a Central Transcriptional Regulator in the A-Factor Regulatory Cascade That Leads to Morphological Development and Secondary Metabolism in Streptomyces griseus
- Isolation of DNA Fragments Bound by Transcriptional Factors, AdpA and ArpA, in the A-Factor Regulatory Cascade
- Increased Cellulose Production from Sucrose by Acetobacter after Introducing the Sucrose Phosphorylase Gene
- Gene Organization in a 12-Kilobase Region Covering afsA Encoding an A-Factor Biosynthetic Enzyme
- Characterization of the Biosynthetic Pathway of Cellulose from Glucose and Fructose in Acetobacter xylinum
- Thermoelectric Properties of Solution Grown β-FeSi_2 Single Crystals
- Characterization of Recombinant β-Amylases from Oryza sativa
- Transformation of Acetobacter polyoxogenes with Plasmid DNA by Electroporation
- The aarC Gene Responsible for Acetic Acid Assimilation Confers Acetic Acid Resistance on Acetobacter aceti
- Specific Excretion into the Medium of a Serine Protease from Serratia marcescens(Microbiology & Fermentation Industry)
- Cloning of the β-Isopropylmalate Dehydrogenase Gene from Acetobacter aceti and Its Use for Construction of a New Host-vector System for Acetobacter(Microbiology & Fermentation Industry)
- A Host-Vector System for a Cellulose-Producing Acetobacter Strain
- Preparation of Ammonium Polyphosphate Form II from the System of Ammonium Orthophosphate-Urea
- Purification and Properties of Cellulases from an Alkalophilic Streptomyces Strain(Microbiology & Fermentation Industry)
- Streptomyces Species as Boundary Microorganisms : Eucaryotic Regulatory Systems for Secondary Metabolism and Morphological Differentiation
- Overexpression of a Gene Cluster Encoding a Chalcone Synthase-like Protein Confers Redbrown Pigment Production in Streptomyces griseus
- Secretion by Saccharomyces cerevisiae of Human Apolipoprotein E as a Fusion to Serum Albumin
- High Level Secretion by Saccharomyces cerevisiae of Human Apolipoprotein E as a Fusion to Rhizomucor Rennin
- Suppression of an Ethanol-Sensitive Mutation of Acetobacter pasteurianus by Overexpression of the his1 Gene Encoding Histidinol Phosphate Aminotransferase
- Characterization of Nitrile Hydratase Genes Cloned by DNA Screeing from Rhodococcus erythropolis
- Precursor-Directed Biosynthesis of Curcumin Analogs in Escherichia coli