Acute D-Psicose Administration Decreases the Glycemic Responses to an Oral Maltodextrin Tolerance Test in Normal Adults

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An examination was conducted to verify D-psicose suppressed the elevation of blood glucose and insulin concentration in a dose-dependent manner under the concurrent administration of maltodextrin and D-psicose to healthy humans. Twenty subjects aged 20-39 y, 11 males and 9 females were recruited. A load test of oral maltodextrin was conducted as a randomized single blind study. The subjects took one of five test beverages (7.5g D-psicose alone, 75g maltodextrin alone, 75g maltodextrin +2.5, 5 or 7.5g D-psicose). Blood was collected before an intake and at 30, 60, 90 and 120min after an intake. Intervals of administration were at least 1wk. The load test with 75g maltodextrin showed significant suppressions of the elevation of blood glucose and insulin concentration under the doses of 5g or more D-psicose with dose dependency. An independent administration of 7.5g D-psicose had no influence on blood glucose or insulin concentration. D-Psicose is considered efficacious in the suppression of the elevation of blood glucose concentration after eating in humans.
日本ビタミン学会の論文