Effects of Voluntary Resistance Exercise and High-protein Snack on Bone Mass, Composition, and Strength in Rats Given Glucocorticoid Injections(Food & Nutrition Sience)
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概要
- 論文の詳細を見る
We examined the effects of a voluntary resistance exercise (climbing) together with high-protein snacks (60% protein) on bone mass and strength in rats given glucocorticoid-injections (2 mg/kg/day) as a model of age-related osteopenia. Fifty-two male Sprague-Dawley rats, 8 weeks age, were assigned to exercise or sedentary groups. These groups were further divided into groups that received no snack, snack during activity or a snack during rest. All groups were meal-fed 7:30-8:30 h and 19:30-20:30 h and the snack was fed 23:30-0:30 h (active) or 11:30-12:30 h (resting). Energy and protein intake were approximately equal in all groups. The exercise groups were allowed to climb a wire-mesh tower cage (φ20 cm × 200 cm) to drink water from a bottle set at the top. Weight gain during the 8-week experimental period was inhibited by a glucocorticoid-injection. Bone mass and strength were increased by climbing exercise with a high-protein snack, while no effect of snack nor any effect of snack timing was observed. Bone weight, calcium content and protein content were positively correlated to maximum load or structural stiffness. These results suggest that resistance exercise and high-protein supplementation may be a preventive therapy for osteoporosis associated with aging.
- 社団法人日本農芸化学会の論文
- 2003-12-23
著者
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MATSUO Tatsuhiro
Faculty of Agriculture, Kagawa University
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MATSUMOTO Keitaro
Saga Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd
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Doi T
Otsuka Pharmaceutical Co. Saga Jpn
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Okamura Koji
Osaka University Of Health And Sport Sciences
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Nozaki Tsutomu
Faculty Of Agriculture Kagawa University
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Suzuki M
School Of Sport Sciences Waseda University
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Suzuki Masashige
School Of Sport Sciences Waseda University
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Matsuo Tatsuhiro
Faculty Of Agriculture Kagawa University
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Matsumoto Keitaro
Saga Nutraceuticals Research Institute Otsuka Pharmaceutical Co.
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DOI Tatsuya
Saga Research Institute, Otsuka Pharmaceutical Co.
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GOHTANI Shoich
Faculty of Agriculture, Kagawa University
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Doi Tatsuya
Saga Nutraceuticals Res. Inst.
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Suzuki Masataka
School Of Sport Sciences Waseda University
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Gohtani Shoich
Faculty Of Agriculture Kagawa University
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