Production of (S)-2-Chloropropionate by Asymmetric Reduction of 2-Chloroacrylate with 2-Haloacrylate Reductase Coupled with Glucose Dehydrogenase(BIOCHEMICAL ENGINEERING)

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概要

• 論文の詳細を見る

• (S)-2-Chloropropionate is a synthetic intermediate for phenoxypropionic acid herbicides. We constructed a system for asymmetric reduction of 2-chloroacrylate to produce (S)-2-chloropropionate with recombinant Escherichia coli cells producing 2-haloacrylate reductase from Burkholderia sp. WS and an NADPH regeneration system. The system provided 37.4 g/l (S)-2-chloropropionate in more than 99.9% e.e.

• 社団法人日本生物工学会の論文
• 2008-04-25

著者

• Mowafy Amr

  Institute For Chemical Research Kyoto University

• Kurihara T

  Laboratory Of Applied Biological Chemistry Department Of Synthetic Chemistry And Biological Chemistr

• Esaki Nobuyoshi

  Kyoto Univ.

• Esaki Nobuyoshi

  Nstitute For Chemical Research Kyoto University

• Kurata Atsushi

  Institute for Chemical Research, Kyoto University

• Fujita Michiyo

  Institute for Chemical Research, Kyoto University

• Kamachi Harumi

  Corporate R&D Center, Showa Denko KK

• Kurihara Tatsuo

  Institute for Chemical Research, Kyoto University

• Esaki Nobuyoshi

  Institute for Chemical Research, Kyoto University

• Kurihara T

  Institute For Chemical Research Kyoto University

• Esaki Nobuyoshi

  Inst. For Chemical Res. Kyoto Univ.

• Fujita Michiyo

  Institute For Chemical Research Kyoto University

• Kamachi Harumi

  Corporate R&d Center Showa Denko Kk

• Kurata Atsushi

  Institute For Chemical Research Kyoto University

• Esaki N

  Kyoto Univ.

• Kurihara T

  Kyoto Univ. Kyoto

• Esaki Nobuyoshi

  Kyoto Univ. Kyoto Jpn

• Esaki Nobuyoshi

  Institute For Chemical Resarch Kyoto University

• Kurihara Tatsuo

  Institute For Chemical Research Kyoto University

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