A New Family of NAD(P)H-Dependent Oxidoreductases Distinct from Conventional Rossmann-Fold Proteins

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概要

• 論文の詳細を見る

• A new family of NAD(P)H-dependent oxidoreductases is now recognized as a protein family distinct from conventional Rossmann-fold proteins. Numerous putative proteins belonging to the family have been annotated as malate dehydrogenase (MDH) or lactate dehydrogenase (LDH) according to the previous classification as type-2 malate/L-lactate dehydrogenases. However, recent biochemical and genetic studies have revealed that the protein family consists of a wide variety of enzymes with unique catalytic activities other than MDH or LDH activity. Based on their sequence homologies and plausible functions, the family proteins can be grouped into eight clades. This classification would be useful for reliable functional annotation of the new family of NAD(P)H-dependent oxidoreductases.

• 社団法人日本生物工学会の論文
• 2005-06-25

著者

• Kurihara Tatsuo

  京都大学化学研究所 分子微生物科学

• Kurihara T

  Laboratory Of Applied Biological Chemistry Department Of Synthetic Chemistry And Biological Chemistr

• Kurihara Tatsuo

  Laboratory Of Microbial Biochemistry Institute For Chemical Research Kyoto University

• Esaki N

  Institute For Chemical Research Kyoto University

• Esaki Nobuyoshi

  Kyoto Univ.

• Esaki Nobuyoshi

  Nstitute For Chemical Research Kyoto University

• Esaki Nobuyoshi

  京都大学化学研究所 分子微生物科学

• Ezaki Nobuyoshi

  Laboratory Of Microbial Biochemistry Institute For Chemical Research Kyoto University

• Kurihara Tatsuo

  Institute for Chemical Research, Kyoto University

• Esaki Nobuyoshi

  Institute for Chemical Research, Kyoto University

• Kurihara T

  Institute For Chemical Research Kyoto University

• GOTO Masaru

  Graduate School of Science, Osaka City University

• MIHARA Hisaaki

  Institute for Chemical Research, Kyoto University

• MIYAHARA Ikuko

  Graduate School of Science, Osaka City University

• HIROTSU Ken

  Graduate School of Science, Osaka City University

• MIYAHARA Ikuko

  Department of Chemistry, Graduate School of Science, Osaka City University

• HIROTSU Ken

  Department of Chemistry, Graduate School of Science, Osaka City University

• Esaki Nobuyoshi

  Inst. For Chemical Res. Kyoto Univ.

• Kurihara Tatsuo

  Inst. For Chemical Res. Kyoto Univ.

• Goto Masaru

  Department Of Electrical Electronics And Information Engineering Graduate School Of Engineering Osak

• Goto Masaru

  Graduate School Of Science Osaka City University

• Goto Masaru

  Department Of Chemistry Graduate School Of Science Osaka City University

• Mizuno Haruo

  Departments Of Pediatrics And Neonatology Nagoya City University Graduate School Of Medical Sciences

• Mizuno Haruo

  Department Of Biotechnology Graduate School Of Engineering Osaka University

• Mizutani H

  Dep. Of Biotechnology Coll. Of Life Sciences Ritsumeikan Univ.

• MURAMATSU Hisashi

  Institute for Chemical Research, Kyoto University

• Esaki N

  Kyoto Univ.

• Kurihara T

  Kyoto Univ. Kyoto

• Esaki Nobuyoshi

  Kyoto Univ. Kyoto Jpn

• Esaki Nobuyoshi

  Institute For Chemical Resarch Kyoto University

• Mizutani Hisashi

  Department Of Chemistry Faculty Of Science Osaka City University

• Matsubara Hiroshi

  Institute For Chemical Research Kyoto University

• Hirotsu Ken

  Graduate School Of Science Osaka City University

• Hirotsu Ken

  Department Of Chemistry Faculty Of Science Osaka City University

• Miyahara Ikuko

  Department Of Chemistry Faculty Of Science Osaka City University

• Mizuguchi H

  Department Of Biochemistry Osaka Medical College

• Murai Hiroki

  名古屋市立大学 医学研究科新生児･小児医学分野

• Kurihara Tatsuo

  Institute For Chemical Research Kyoto University

• Murai Hiroki

  Department Of Pediatrics And Neonatology Nagoya City University Graduate School Of Medical Sciences

• Mihara Hisaaki

  Institute For Chemical Research Kyoto University

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