Inhibitory Effect of Schizandrin on Passive Cutaneous Anaphylaxis Reaction and Scratching Behaviors in Mice(Pharmacognosy)
スポンサーリンク
概要
- 論文の詳細を見る
To evaluate the antiallergic effect of the fruit of Schizandra chinensis BAILL (Family Magnoliaceae), which inhibited the mouse passive cutaneous anaphylaxis (PCA) reaction in a preliminary experiment, its main constituent, schizandrin, was isolated and its antiallergic effect investigated. Schizandrin inhibited the PCA reaction induced by the IgE-antigen complex, the scratching behaviors induced by compound 48/80 and the serum IgE production induced by ovalbumin. Schizandrin also inhibited the in vitro degranulation of compound 48/80-induced rat peritoneal mast cells and IgE-induced RBL 2H3 cells. Schizandrin reduced the protein expressions of TNF-α and IL-4 in IgE-induced RBL 2H3 cells. These findings suggest that schizandrin can improve IgE-induced anaphylaxis and scratching behaviors.
- 社団法人日本薬学会の論文
- 2007-06-01
著者
-
Shin Yong
College Of Pharmacy Kyung Hee University
-
Kim Dong-hyun
College Of Pharmacy Kyung Hee University
-
BAE Ki-Hwan
College of Pharmacy, Chungnam National University
-
LEE Bomi
College of Pharmacy, Kyung Hee University
-
BAE Eun-Ah
College of Pharmacy, Kyung Hee University
-
TRINH Hien
College of Pharmacy, Kyung Hee University
-
SHIN Yong-Wook
College of Pharmacy, Kyung Hee University
-
PHUONG Thien
College of Pharmacy, Chungnam National University
-
Bae Eun-ah
韓国
-
Bae Eun-ah
College Of Pharmacy Kyung Hee University
-
Phuong Thien
韓国
-
Phuong Thien
College Of Pharmacy Chungnam National University
-
Bae Ki
韓国
-
Bae Ki-hwan
College Of Pharmacy Chungnam National University
-
Shin Yong-wook
College Of Pharmacy Kyung Hee University
-
Choo Min-kyung
韓国
-
Shin Yong‐wook
韓国
-
Kim D‐h
College Of Pharmacy Kyung Hee University
-
Bae E‐a
College Of Pharmacy Kyung Hee University
-
Lee Bomi
韓国
-
Bae Eun-ah
Department Of Life And Nanopharmaceutical Sciences And Department Of Pharmaceutical Science Kyung He
-
Han Myung
Dep. Of Food And Nutrition Kyung Hee Univ.
-
Kim D‐h
Taegu Univ. Kyungbuk Kor
-
Bae Ki-hwan
College Of Pharmacy Chung-nam University
-
Trinh Hien
College Of Pharmacy Kyung Hee University
-
Kim Dong-hyun
College Of Pharmacy
関連論文
- Anti-Helicobacter pylori Acticvity of Quinolone Alkaloids from Evodiae Fructus
- Magnolol and Honokiol : Inhibitors against Mouse Passive Cutaneous Anaphylaxis Reaction and Scratching Behaviors(Pharmacology)
- Inhibitory Effect of Schizandrin on Passive Cutaneous Anaphylaxis Reaction and Scratching Behaviors in Mice(Pharmacognosy)
- In Vitro and in Vivo Antiallergic Effect of the Fructus of Evodia rutaecarpa and Its Constituents(Pharmacognosy)
- Intestinal Bacteria Activate Estrogenic Effect of Main Constituents Puerarin and Daidzin of Pueraria thunbergiana(Pharmacognosy)
- Inhibitory Effects of Korean Red Ginseng and Its Genuine Constituents Ginsenosides Rg3, Rf, and Rh2 in Mouse Passive Cutaneous Anaphylaxis Reaction and Contact Dermatitis Models(Pharmacology)
- Effect of Chunghyuldan in Chronic Oxazolone-Induced Mouse Dermatitis(Pharmacology)
- Ginsenoside Rh2 Reduces Ischemic Brain Injury in Rats (Pharmacognosy)
- Antithrombotic and Antiallergic Activities of Daidzein, a Metabolite of Puerarin and Daidzin Produced by Human Intestinal Microfiora(Pharmacognosy)
- Metabolism of Ginsenoside R_c by Human Intestinal Bacteria and Its Related Antialiergic Activity
- Metabolism of Kalopanaxsaponin K by Human Intestinal Bacteria and Antirheumatoid Arthritis Activity of Their Metabolites
- Metabolism of 20(S)-and 20(R)-Ginsenoside R_ by Human Intestinal Bacteria and Its Relation to in Vitro Biological Activities
- In Vitro Inhibitory Effect of Some Flavonoids on Rotavirus Infectivity
- Metabolism of Rhaponticin and Chrysophanol 8-o-β-D-Glucopyranoside from the Rhizome of Rheum undulatum by Human Intestinal Bacteria and Their Anti-allergic Actions
- Inhibitory Effect of Herbal Medicines on Rotavirus Infectivity
- Metabolism of 6"-O-Xylosyltectoridin and Tectoridin by Human Intestinal Bacteria and Their Hypoglycemic and in Vitro Cytotoxic Activities
- Metabolism of Quercitrin by Human Intestinal Bacteria and Its Relation to Some Biological Activities
- Anti-Helicobacter pylori Activity of the Metabolites of Poncirin from Poncirus trifoliata by Human Intestinal Bacteria
- Anti-Helicobacter pylori Activity of Hearbal Medicines
- Metabolism of Puerarin and Daidzin by Human Intestinal Bacteria and Their Relation to in Vitro Cytotoxicity
- Metabolism of Kalopanaxsaponin B and H by Human Intestinal Bacteria and Antidiabetic Activity of Their Metabolites
- Constitutive β-Gluccosidases Hydrolyzing Ginsenoside R_ and R_ from Human Intestinal Bacteria
- β-Glucuronidase-Inhibitory Activity and Hepatoprotective Effect of Ganoderma lucidum
- Metabolism of Ginsenoside Re by Human Intestinal Microflora and Its Estrogenic Effect(Pharmacognosy)
- Purification and Characterization of Ginsenoside R_-Metabolizing β-Glucosidase from Fusobacterium K-60,a Human Intestinal Anaerobic Bacterium
- Stereospecific Effects of Ginsenoside Rg_3 Epimers on Swine Coronary Artery Contractions(Pharmacology)
- Anti-inflammatory and Anti-nociceptive Effects of the Methanol Extract of Fomes fomentarius(Pharmacognosy)
- P-25 マウス結腸がん細胞におけるNF-κB活性化とがん転移に対する人参代謝産物の抑制効果(腫瘍,一般演題ポスター,第24回和漢医薬学会大会 和漢薬の複雑さ-経験知と科学知-)
- Inhibitory Effect of Chunghyuldan in Prostaglandin E2 and Nitric Oxide Biosynthesis of Lipopolysaccharide-Induced RAW 264.7 Cells(Pharmacognosy)
- Metabolic Activities of Ginsenoside Rb1, Baicalin, Glycyrrhizin and Geniposide to Their Bioactive Compounds by Human Intestinal Microflora(Pharmacognosy)
- Selective Cytotoxic Activity of Valinomycin against HT-29 Human Colon Carcinoma Cells via Down-Regulation of GRP78(Pharmacology)
- Antipruritic Effect of Ginsenoside Rb1 and Compound K in Scratching Behavior Mouse Models
- Hepatoprotective Effect of Tectoridin and Tectorigenin on tert-Butyl Hyperoxide-Induced Liver Injury
- Hepatoprotective Effects of Irisolidone on tert-Butyl Hyperoxide-Induced Liver Injury(Pharmacognosy)
- Inhibitory Effect of Ginsenoside Rb1 and Compound K on NO and Prostaglandin E2 Biosyntheses of RAW264.7 Cells Induced by Lipopolysaccharide(Pharmacognosy)
- Passive Cutaneous Anaphylaxis-Inhibitory Action of Tectorigenin, a Metabolite of Tectoridin by Intestinal Microflora(Pharmacognosy)
- Metabolism of Chiisanoside from Acanthopanax divaricatus var.albeofructus by Human Intestinal Bacteria and Its Relation to Some Biological Activities
- 5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone : A Pancreatic Lipase Inhibitor Isolated from Alpinia officinarum(Pharmacognosy)
- 3-Methylethergalangin Isolated from Alpinia officinarum Inhibits Pancreatic Lipase
- Antiallergic Activity of Ginsenoside Rh2(Pharmacognosy)
- Purification and Reaction Mechanism of Arylsulfate Sulfotransferase from Haemophilus K-12, a Mouse Intestinal Bacterium
- Transformation of Ginsenosides Rb2 and Rc from Panax ginseng by Food Microorganisms(Pharmacognosy)
- Bacteroides J-37,a Human Intestinal Bacterium, Produces α-Glucuronidase
- D-34 Clinical and Microbiological Studies on the Effect of Magnoliae cortex Extracts Containing Dentifrice in Gingivitis
- Estrogenic Effect of Main Components Kakkalide and Tectoridin of Puerariae Flos and Their Metabolites(Pharmacognosy)
- Cloning, Expression and Purification of Arylsulfate Sulfotransferase from Eubacterium A-44(Biochemistry)
- Protective Effects of Kakkalide From Flos Puerariae on Ethanol-Induced Lethality and Hepatic Injury Are Depaendent on Its Biotransformation by Human Intestinal Microflora
- 韓国における職業がんの推計
- Estimates of Occupational Cancer in Korea
- Biotransformation of Glycyrrhizin to 18β-Glycyrrhetinic Acid-3-O-β-D-glucuronide by Streptococcus LJ-22,a Human Intestinal Bacterium
- Purification and Characterization of α-L-Rhamnosidase from Bacteroides JY-6,a Human Intestinal Bacterium
- Cloning and Sequencing of the Klebsiella K-36 astA Gene, Encoding an Arylsulfate Sulfotransferase
- Purification and Characterization of a Novel Heparinase from Bacteroides stercoris HJ-15
- Purification and Characterization of Ginsenoside Ra-Hydrolyzing β-D-Xylosidase from Bifidobacterium breve K-110, a Human Intestinal Anaerobic Bacterium(Biochemistry/Molecular Biology)
- Purification and Characterization of β-Glucosidase from Bacteroides JY-6,a Human Intestinal Bacterium