Anti-Helicobacter pylori Activity of the Metabolites of Poncirin from Poncirus trifoliata by Human Intestinal Bacteria
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概要
- 論文の詳細を見る
Poncirin was isolated from water extract of the fruits of Poncirus trifoliata and metabolized by human intestinal bacteria. The inhibitory effect of poncirin and its metabolites by these bacteria on the growth of Helicobacter pylori (HP) was investigated. Among them, ponciretin (5,7-dihydroxy-4'-methoxyflavanone), the main metabolite most potently inhibited the growth of HP, with a minimum inhibitory concentration (MIC) of 10-20 μg/ml. However, poncirin and its metabolites except ponciretin did not inhibit the growth of HP, nor did they inhibit HP urease.
- 社団法人日本薬学会の論文
- 1999-04-15
著者
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Shin Yong
College Of Pharmacy Kyung Hee University
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Kim Dong-hyun
College Of Pharmacy Kyung Hee University
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BAE Eun-Ah
Department of Life and Nanopharmaceutical Sciences and Department of Pharmaceutical Science, Kyung H
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BAE Eun-Ah
College of Pharmacy, Kyung Hee University
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HAN Myung
Department of Food and Nutrition, Kyung Hee University
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Han Myung
Department Of Food And Nutrition Kyung Hee University
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Bae Eun-ah
韓国
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Bae Eun-ah
Department Of Food And Nutrition Kyung Hee University
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Choo Min-kyung
College Of Pharmacy Kyung Hee University
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Choo Min-kyung
韓国
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Shin Yong‐wook
韓国
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Kim D‐h
College Of Pharmacy Kyung Hee University
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Bae E‐a
College Of Pharmacy Kyung Hee University
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Bae Eun-ah
Department Of Life And Nanopharmaceutical Sciences And Department Of Pharmaceutical Science Kyung He
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Han Myung
Dep. Of Food And Nutrition Kyung Hee Univ.
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Kim D‐h
Taegu Univ. Kyungbuk Kor
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Kim Dong-hyun
College Of Pharmacy
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