Metabolism of Puerarin and Daidzin by Human Intestinal Bacteria and Their Relation to in Vitro Cytotoxicity
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概要
- 論文の詳細を見る
When puerarin or daidzin were incubated for 24h with human intestinal bacteria, two metabolites, daidzein and calycosin, were produced from them, respectively. The metabolic time course of puerarin was as follows : at an early time, puerarin was converted to daidzin, and then calycosin. The metabolic time course of daidzin by human intestinal bacteria was also similar to that of puerarin. The in vitro cytotoxicities of these metabolites, calycosin and dadizein, were superior to those of puerarin and daidzein.
- 社団法人日本薬学会の論文
- 1998-06-15
著者
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Shin Yong
College Of Pharmacy Kyung Hee University
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Kim Dong-hyun
College Of Pharmacy Kyung Hee University
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BAE Eun-Ah
Department of Life and Nanopharmaceutical Sciences and Department of Pharmaceutical Science, Kyung H
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BAE Eun-Ah
College of Pharmacy, Kyung Hee University
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HAN Myung
Department of Food and Nutrition, Kyung Hee University
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YU Ki-Ung
College of Pharmacy
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Han Myung
Department Of Food And Nutrition Kyung Hee University
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Bae Eun-ah
韓国
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Bae Eun-ah
Department Of Food And Nutrition Kyung Hee University
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Choo Min-kyung
College Of Pharmacy Kyung Hee University
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Choo Min-kyung
韓国
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Shin Yong‐wook
韓国
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Kim D‐h
College Of Pharmacy Kyung Hee University
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Bae E‐a
College Of Pharmacy Kyung Hee University
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Yu Ki-ung
College Of Pharmacy:kyung-hee University
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Bae Eun-ah
Department Of Life And Nanopharmaceutical Sciences And Department Of Pharmaceutical Science Kyung He
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Han Myung
Dep. Of Food And Nutrition Kyung Hee Univ.
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Kim Dong-hyun
Department Of Life And Nanopharmaceutical Sciences And Department Of Pharmaceutical Science Kyung He
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Kim D‐h
Taegu Univ. Kyungbuk Kor
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Kim Dong-hyun
College Of Pharmacy
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