Rearrangement in Dihydroresorcinol Derivatives. VIII. Beckmann Rearrangement versus Semmler-Wolff Aromatization of 3-Acylamino-2-cyclohexen-1-one Oximes
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概要
- 論文の詳細を見る
Beckmann rearrangement of 1,2,3,4,5,6,7,8-octahydro-2,5-dioxoquinoline oxime (Ia, b) and 1,2,3,4,5,6,7,10-octahydro-2,7-dioxoquinoline oximes (VIa, b) with PPA gives 1,2,3,-4,5,6,7,8,9-nonahydro-2,5-dioxopyrido [3,2-c] azepine (IIa, b) and 1,2,3,4,5,6,7,8,10-nonahydro-2,8-dioxopyrido [2,3-d] azepine (VIIa, b), respectively. Under the same reaction conditions, 3-acetylamino-2-methyl-2-cyclohexen-1-one oxime (X) and 1-acetyl-1,2,3,4,5,6,7,8-octahydro-5-oxoquinoline oxime (XIII) undergo a Semmler-Wolff aromatization to give 2-methyl-1,3-phenylenediamine (XI) and 5-amino-1,2,3,4-tetrahydroquinoline (XIV), respectively.
- 公益社団法人日本薬学会の論文
- 1972-05-25
著者
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田村 恭光
Faculty Of Pharmaceutical Sciences Osaka University
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北 泰行
Faculty Of Pharmaceutical Sciences Osaka University
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浦岡 順子
Faculty Of Pharmaceutical Sciences Osaka University
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