覚せい剤及び関連化合物の代謝 : その生化学的側面
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概要
- 論文の詳細を見る
The enzyme systems and the mechanisms involved in the biotransformation of amphetamine, methamphetamine and the related compounds are briefly reviewed. The major themes discussed in this review are : 1) cytochrome P-450 isozymes involved in the deamination, N-dealkylation and aromatic hydroxylation ; 2) the role of cytochrome P-450 and flavin-containing monooxygenase in the N-dealkylation ; 3) the enzymes functioning as hydroxylamine reductase and oxidase ; 4) molecular mechanisms of deamination and N-dealkylation ; 5) metabolic-intermediate complex.
- 社団法人日本薬学会の論文
- 1989-12-31
著者
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山田 英之
九州大学薬学部
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山田 英之
九州大学 院 薬
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吉村 英敏
中村学園大・食物栄養
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吉村 英敏
九州大学薬学部
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Yoshimura Hidetoshi
Department Of Food And Nutrition Nakamura Gakuen University
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