トキシコロジーと薬物代謝学(薬学におけるトキシコロジーの発展)
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概要
- 論文の詳細を見る
- 公益社団法人日本薬学会の論文
- 1982-07-01
著者
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吉村 英敏
中村学園大・食物栄養
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吉村 英敏
九州大学薬学部
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Yoshimura Hidetoshi
Department Of Food And Nutrition Nakamura Gakuen University
関連論文
- Effect of Morphine and Its Conjugates on the Isolated Ileal Preparation of Guinea-pig
- 薬物動態研究事始め(4)
- 学術貢献賞受賞 山本郁男氏の業績
- 医薬品の生体内変化に関する研究(第85報)1-p-Chlorophenyl-2,3-dimethyl-4-dimethylaminobutan-2-ol Hydrochlorideの代謝に関する研究
- Properties of Nitrofuran Reductases from Escherichia coli B/r
- Identification of in Vitro Metabolites of 2,4,6,2', 4', 6'-Hexachlorobiphenyl from Phenobarbital-Treated Dog Liver Microsomes
- Synthesis and Pharmacological Evaluation in Mice of Halogenated Cannabidiol Derivatives
- Pharmacologica Efects in Mice of Anandamide and Its Related Fatty Acid Ethanolamides, and Enhancement of Cataleptogenic Effect of Anandamide by Phenylmethylsulfonyl Fluoride
- Synthesis and Pharmacological Activities in Mice of Halogenated Δ^9-Tetrahydrocannabinol Derivatives
- BrucineによるCYP2B subfamily P450の誘導:種差による検討
- フェノバルビタール型PCBのウサギ肝における代謝
- Effect of Cytochrome P450 Inducers on Liver Microsomal Metabolism of Tetrachlorobiphenyls in Rats, Guinea Pigs and Hamsters
- Metabolic Formation of Dimethylamine and Methylamine from Basic Drugs Containing N-Methyl Group : A Newly Established Chromatographic Assay and Its Application to the Determination of Deaminase Activity
- Purification and Characterization of a Morphine UDP-Glucuronyltransferase Isoform from Untreated Rat Liver
- A New Metabolite of 2,4,3', 4'-Tetrachlorobiphenyl in Rat Feces
- Synthesis and Pharmacological Activity of Sulfate Conjugates at 6-Position of N-Substituted Normorphine Derivatives
- Rat Liver DT-Diaphorase as a Nitroso-Reductase
- 覚せい剤及び関連化合物の代謝 : その生化学的側面
- Synthesis and Analgesic Effect of Normorphine-3- and -6-glucuronides
- 乱用薬物の代謝
- 駆け出しの頃(私はあの時、こう閃いた!-研究の壁を突破し、大きく飛躍するため-)
- モルヒネとヘロインの法中毒学
- Reconstitution of Apo-DT-diaphorase with Flavin-Adenine Dinucleotide
- CIS-TRANS ISOMERIZATION OF A NITROFURAN AF-2 BY RAT LIVER MICROSOMAL PREPARATIONS
- 共通一次入試と学生気質(入試制度と薬学教育)
- 薬物代謝からみた中毒 (プライマリ・ケアのための急性中毒の救急初期治療)
- REDUCTION OF METHYL 5-NITRO-2-FUROATE BY XANTHINE OXIDASE : AN EVIDENCE FOR HYDROXYLAMINOFURAN FORMATION
- 大麻幻覚成分Δ^9-Tetrahydrocannabinolのヒト尿中主代謝物Δ^9-Tetrahydrocannabinol-11-oic AcidのGC-MSによる定性・定量
- Metabolism of Drugs. LXXIII. The Metabolic Fate of Nitrofuran Derivatives. (1) Studies on the Absorption and Excretion
- Metabolism of Drugs. LXX. Further Study on Antipyrine Metabolism
- 医薬品の生体内変化に関する研究(第71報) : アミノピリンの代謝について
- 医薬品の生体内変化に関する研究(第68報) : メタプロテレノールの代謝について1
- 医薬品の生体内変化に関する研究(第66報) : Pantethineの生体内変化について
- ライスオイル中毒症(いわゆる油症)特にその原因毒物の化学的究明について
- 大麻草の裁判化学的研究III. : 大麻成分検出法の実際鑑定への応用(2)
- 大麻草の裁判化学的研究II. : 大麻成分検出法の実際鑑定への応用(1)
- メチルオレンジ法によるモルヒネ定量の変法
- 医薬品の生体内変化に関する研究(第58報) : 4-ブチルアミノアンチピリンの生体内変化について
- Microsomal Aldehyde Oxygenase (MALDO) for Tolualdehydes, Active Metabolites of Xylenes, in the Mouse Liver and Lung
- "B-4 Hydrolysis of Xenobiotics by ES46.5K, a Novel Esterase from Mouse Liver Microsomes
- Microsomal Aldehyde Oxygenase (MALDO): Purification and Characterization of a Cytochrome P450 Isozyme Responsible for Oxidation of 9-Anthraldehyed to 9-Anthracenecarboxylic Acid in Monkey Liver
- Mechanism of Inhibitory Effects of Cannabidiol and Cannabidiol Hydroxy-quinone on the Hepatic Microsomal Drug-Metabolizing Enzymes in Mice (Proceedings of the 23rd Symposium on Toxicology and Environmental Health)
- Involvement of a Novel Mouse Hepatic Microsomal Esterase, ES46.5K, in the Hydrolysis of Phthalate Esters
- Mechanism of Hepatic Microsomal Oxidation of 11-Hydroxy-Δ^8-tetra-hydrocannabinol to 11-Oxo-Δ^8-tetrahydrocannabinol. Evidence for Hydration of the Aldehyde Formed
- PURIFICATION AND CHARACTERIZATION OF MOUSE HEPATIC MICROSOMAL ALDEHYDE OXYGENASE
- MECHANISM OF CANNABIELSOIN FORMATION FROM CANNABIDIOL, ONE OF THE MAJOR CMPONENTS OF MARIHUANA
- CYTOCHROME P450 ISOZYMES INVOLVED IN METABOLIC ACTIVATION OF Δ^9-TETRAHYDROCANNABINOL BY RAT LIVER MICROSOMES
- Mechanism of Biological Formation of Cannabielsoin from Cannabidiol in the Guinea-Pig, Mouse, Rat and Rabbit
- HEPATIC MICROSOMAL OXYGENATION OF METHYL GROUP TO CARBOXYLIC ACID IN XENOBIOTICS : METABOLISM OF Δ^8-TETRAHYDROCANNABINOL AT THE 11-POSITION
- Identification of Cannabielsoin, a New Metabolite of Cannabidiol Formed by Guinea-Pig Hepatic Microsomal Enzymes, and Its Pharmacological Activity in Mice
- METABOLIC DISPOSITION OF 8α, 9α-AND 8β, 9β-EPOXYHEXAHYDROCANNABINOLS IN THE MOUSE
- DIFFERENCE IN EPOXIDES FORMATION AND THEIR FURTHER METABOLISM BETWEEN Δ^9 -AND Δ^8-TETRAHYDROCANNABINOLS BY HUMAN LIVER MICROSOMES
- Morphine Phosphate Estersの合成ならびに薬理作用について
- ノスカピンの生体内運命に関する研究(第1報)家兎尿中代謝物の検索
- 油症研究-この10年間の推移
- ポリ塩素化ビフェニル(PCB)と関連化合物 (環境汚染物質と毒性--有機物質編)
- Metabolism of Drugs. LXXXI. Further Studies on Metabolism of Prolintane in Rabbits
- Metabolism of Drugs. LXXVI. The Metabolic Fate of Prolintane in Rabbits
- 大麻主成分Δ^9-Tetrahydrocannabinol(Δ^9-THC)およびCannabidiol(CBD)のPentobarbital睡眠および肝薬物代謝酵素系に及ぼす影響-マウスにおける性差
- Anandamide, an Endogenous Cannabinoid Receptor Ligand, Also Interacts with 5-Hydroxytryptamine (5-HT) Receptor
- 医薬品の生体内変化に関する研究(第74報)メタプロテレノールの代謝について2
- Metabolism of Drugs. LXXV. The Enzymatic Degradation of Isoprophenamine
- Metabolism of Drugs. LXXX. The Metabolic Fate of Nitrofuran Derivatives. (3). Studies on Enzymes in Small Intestinal Mucosa of Rat Catalyzing Degradation of Nitrofuran Derivatives
- Metabolism of Drugs. LXXIX. The Metabolic Fate of Nitrofuran Derivatives. (2). Degradation by Small Intestinal Mucosa and Absorption from Gastrointestinal Tract
- Susceptibility of Aromatic Nitro Compounds to Xanthine Oxidase-catalyzed Reduction
- トキシコロジーと薬物代謝学(薬学におけるトキシコロジーの発展)
- オクテット
- Chemical Reactivity of Morphine and Morphine-6-conjugates and Their Binding to Rat Brain
- 医薬品の生体内変化に関する研究(第84報)Morphine Glucuronidesのウサギ, モルモットおよびマウスにおける代謝
- 医薬品の生体内変化に関する研究(第83報)Morphine Glucuronidesのラットにおける代謝
- 医薬品の生体内変化に関する研究(第77報)アンチピリンのin Vitro代謝
- INHIBITORY EFFECT OF CANNABIDIOL ON THE HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEM IN THE RAT
- ヨウ化白金酸カリウムによるモルヒネの瑩光反応ならびにその検出法への応用
- 大麻成分の代謝と薬理作用
- DEAMINATION OF AMPHETAMINES BY CYTOCHROMES P450: STUDIES ON SUBSTRATE SPECIFICITY AND REGIOSELECTIVITY WITH MICROSOMES AND PURIFIED CYP2C SUBFAMILY ISOZYMES
- Induction of Bilirubin UDP-Glucuronyltransferase and P-450 4A Subfamily in Guinea Pigs by Treatment with Coplanar PCB (Proceedings of the 18th Symposium on Toxicology, and Environmental Health)
- Mechanism of Pulmonary Cytochrome P450 Inactivation by Tolualdehydes, Active Metabolites of Xylenes (Proceedings of the 22nd Symposium on Toxicology and Environmental Health)
- Metabolic Reaction of Tolualdehydes by Microsomal Aldehyde Oxygenase (MALDO) in Lung (Proceedings of the 19th Symposium on Toxicology and Environmental Health)
- Effect of Coplanar PCB on Gluconeogenesis and Lipid Metabolism : Comparison between Rats and Guinea Pigs (Proceedings of the 19th Symposium on Toxicology and Environmental Health)
- INHIBITION OF ANANDAMIDE AMIDASE ACTIVITY IN MOUSE BRAIN MICROSOMES BY CANNABINOIDS
- Involvement of a Novel Mouse Hepatic Esterase (ES46.5K) in the Hydrolysis of Phthalate Esters (Proceedings of the 21st Symposium on Toxicology and Environmental Health)
- Studies on Metabolism and Toxicity of Organic Solvents, Toluene and Related Compounds : Metabolism of Benzaldehydes by Microsomal Aldehyde Oxygenase (MALDO) (Proceedings of the 18th Symposium on Toxicology, and Environmental Health)
- 9α, 10α-EPOXYHEXAHYDROCANNABINOL FORMATION FROM Δ^9-TETRAHYDROCANNABINOL BY LIVER MICROSOMES OF PHENOBARBITAL-TREATED MICE AND ITS PHARMACOLOGICAL ACTIVITIES IN MICE
- 大麻成分, テトラヒドロカンナビノール, カンナビジオール及び活性代謝物とシンナー及びその含有成分との相互作用