STUDIES ON BEFUNOLOL REDUCTASE FROM RABBIT LIVER
スポンサーリンク
概要
著者
-
Imamura Yorishige
Faculty Of Pharmaceutical Sciences Kumamoto University
-
OTAGIRI MASAKI
Faculty of Pharmaceutical Science, Kumamoto University
-
樋口 恒彦
東京大学薬学部
-
HIGUCHI Toshiyuki
Faculty of Pharmaceutical Sciences, Kumamoto University
-
NOZAKI Yoshihide
Faculty of Pharmaceutical Sciences, Kumamoto University
-
樋口 恒彦
Waseda Univ.
-
Nozaki Yoshihide
Faculty Of Pharmaceutical Sciences Kumamoto University
-
Otagiri Masaki
Faculty Of Pharmaceutical Science Kumamoto University
関連論文
- ウサギ肝臓カルボニル還元酵素のアセトヘキサミドおよび4-アセチルピリジン誘導体に対する諸性質(発表論文抄録(1994))
- Enzymatic Hydrolysis of the Horn and Hoof of Cow and Buffalo
- ウサギ腎由来のカルボニル還元酵素により触媒されるアセトヘキサミドの還元反応におけるケトン性薬物の抑制効果に関する研究
- Mechanism of Inhibition of Carbonyl Reductase from Rabbit Kidney by Phenylbutazone
- カルボニル還元酵素の単離およびその特性(発表論文抄録(1993))
- Further Studies on Reductive Metabolism of Acetohexamide in Heart
- Oxygen Activation by Iron(III)-Porphyrin/NaBH_4/Me_4N・OH System as Cytochrome P-450 Model. Oxygenation of Olefin, N-Dealkylation of Tertiary Amine, Oxidation of Sulfide, and Oxidative Cleavage of Ether Bond
- INCREASING 5-LIPOXYGENASE INHIBITORY ACTIVITIES BY OXIDATIVE CONVERSION OF O-METHOXYPHENOLS TO CATECHOLS USING A Cu^ - ASCORBIC ACID - O_2 SYSTEM
- Differential Pharmacokinetics of Acetohexamide in Male Wistar-Imamichi and Sprague-Dawley Rats : Role of Microsomal Carbonyl Reductase(Biopharmacy)
- 生体類似型酸化反応系「銅-アスコルビン酸-酸素」系 : フェノール・アニソール類の選択的酸化とその反応機構,および生理活性物質創製への応用
- INCLUSION COMPLEXATIONS OF FLURBIPROFEN WITH β-CYCLODEXTRIN AND TRI-O-METHYL-β-CYCLODEXTRIN
- Interaction Mode of Dicumarol and Its Derivatives with Human Serum Albumin, α_1-Acid Glycoprotein and Asialo α_1-Acid Glycoprotein
- Catalytic Properties for Naphthoquinones and Partial Primary Structure of Rabbit Heart Acetohexamide Reductase.
- Catalytic Properties for Naphthoquinones and Partial Primary Structure of Rabbit Heart Acetohexamide Reductase
- Carbonyl Reductase Purified from Rabbit Liver Is Not the Product of a Carbonyl Reductase Gene (RCBR5 or RCBR6)Cloned from the Rabbit Liver cDNA Libray.
- Carbonyl Reductase Purified from Rabbit Liver Is Not the Product of a Carbonyl Reductase Gene (RCBR5 or RCBR6) Cloned from the Rabbit Liver cDNA Library
- Characterization of Acetohexamide Reductases Purified from Rabbit Liver, Kidney, and Heart: Structural Requirements for Substrates and Inhibitors
- Purifiation and Catalytic Properties of a Novel Acetohexamide-Reducing Enzyme from Rabbit Heart
- Stereoselective Reduction of Acetohexamide in Cytosol of Rabbit Liver
- Stability of a Cisplatin-Chondroitin Sulfate A Complex in Plasma and Kidney in Terms of Protein Binding
- Improved Nitric Oxide Detection Using 2,3-Diaminonaphthalene and Its Application to the Evaluation of Novel Nitric Oxide Synthase Inhibitors
- Sex-Dependent Pharmacokinetics and in Vitro Reductive Metabolism of Acetohexamide in Wistar-Imamichi Rats
- Individual Variation of Acetohexamide Reductase Activities in Liver Microsomes and Cytosol of Rats
- Wistar-Imamichi Rats Exhibit a Strong Resistance to Cadmium Toxicity
- Superoxide Dismutase Activity of Iron(II)TPEN Complex and Its Derivatives
- Dipeptides Containing L-Arginine Analogs : New Isozyme-Selective Inhibitors of Nitric Oxide Synthase
- High-performance liquid chromatography with chemiluminescence detection of penbutolol and its hydroxylated metabolite in rat plasma
- 錯体化学からNO合成酵素の配位構造と反応性の謎に迫る
- Selective Deoxygenation of Heteroaromatic N-Oxides with Olefins Catalyzed by Ruthenium Porphyrin
- 酵素機能に対するポルフィリン配位構造の必然性
- NO合成酵素とシトクロムP450 : その共通点と相違点
- Effects of Methyl 9(or 10)-Hydroxy-10(or 9)-mercaptostearate and Hexanecabethioic S-Acid on Cupric Ion- or 2,2-Azo-bis(2-amidinopropane) Dihydrochloride (AAPH)-Induced Oxidation of Low Density Lipoprotein
- Thiopalmitic Acid-Mediated Fe(III)-Nitrilotriacetate Reduction an Lipid Peroxidation
- シトクロムP450のO-O結合開裂機構をめぐる論争
- 含窒素芳香族複素環N-オキシドールテニウムポルフィリン触媒系による多様な高効率酸化反応
- 触媒補助基の多重導入によるチトクロムP-450モデルの高効率化
- A Novel Aromatic Hydroxylation of Phenolic Compounds with Cu^-Ascorbic Acid-O_2 System
- Application of Chemical P-450 Model Systems to Study Drug Metabolism. III. : Metabolism of 3-Isobutyryl-2-isopropylpyrazolo[1,5-α]pyridine
- "METABOLIC ACTIVATION" OF o-METHOXYPHENOLS VIA O-DEMETHYLATION WITH A Cu^ -ASCORBIC ACID-O_2 SYSTEM AS A FUNCTIONAL MODEL OF CYTOCHROME P-450
- FACILE PREPARATION OF UNSTABLE METABOLIC INTERMEDIATES : EPOXIDE(S) OF PYRAZOLO[1,5-a]PYRIDINE DERIVATIVES BY THE CYTOCHROME P-450 CHEMICAL MODEL
- 60 2-オキサゾロンを構築材とする1、2-アミノアルコール類の効率合成(口頭発表の部)
- Effects of Repeated Clarithromycin Administration on the Pharmacokinetic Properties of Pindolol in Rats
- Effects of α_1-Acid Glycoprotein on Erythrocyte Deformability and Membrane Stabilization(Biopharmacy)
- Characterization of Ligand Binding Sites on the α_1-Acid Glycoprotein in Humans, Bovines and Dogs
- EFFECT OF REPEATED ADMINISTRATION OF PYRIDINOLCARBAMATE ON THE RENAL EXCRETION OF SOME DRUGS IN RABBITS
- Characterization of a Binding Site of UCN-01,a Novel Anticancer Drug on α_1-Acid Glycoprotein
- Genetic Evidence of Resistance to Cadmium Toxicity in Wistar-Imamichi Rats
- Inclusion Complex of 3,9-Bis(N, N-dimethylcarbamoyloxy)-5H-benzofuro[3,2-c]quinoline-6-one (KCA-098) with Heptakis(2,6-di-O-methyl)-β-cyclodextrin : Interaction and Dissolution Properties
- Effect of Grinding with Hydroxypropyl Cellulose on the Dissolution and Particle Size of a Poorly Water-Soluble Drug
- Inhibitory Effects of Flavonoids on Rabbit Heart Carbonyl Reductase
- Enzymatic Synthesis of (-)- and (+)-Acetoxyhexamides and (-)- and (+)-Hydroxyhexamides
- Inhibition of Rabbit Heart Carbonyl Reductase by Fatty Acids
- Purification and Catalytic Properties of a Tetrameric Carbony1 Reductase from Rabbit heart
- STUDIES ON BEFUNOLOL REDUCTASE FROM RABBIT LIVER
- In Vivo and in Vitro Binding of (-)-Hydroxyhexamide, a Major Metabolite of Acetohexamide, to Rabbit Serum
- Metabolic Reduction of Acetohexamide in Rat Kidney : Sex Difference and Effect of Streptozotocin-Induced Diabetes
- SEX DIFFERENCE OF ACETOHEXAMIDE REDUCTION IN RAT LIVER
- EFFECTS OF VARIOUS FACTORS ON METABOLIC REDUCTION OF ACETOHEXAMIDE
- REDUCTION OF ACETOHEXAMIDE BY RABBIT HEART CYTOSOL
- Effect of Phenylbutazone on Serum Protein Binding and Pharmacokinetic Behavior of Sulfadimethoxine in Rabbits, Dogs and Rats
- SPECIES DIFFERENCE IN PROTEIN BINDING DISPLACEMENT OF SULFADIMETHOXINE
- EFFECT OF PHENYLBUTAZONE ON SERUM PROTEIN BINDING OF SULFADIMETHOXINE IN DIFFERENT ANIMAL SPECIES
- MODEL ANALYSIS OF INTERFACIAL TRANSFER AND ABSORPTION BEHAVIOR OF DRUG FOLLOWING DISSOLUTION FROM COMPRESSED TABLET : IN THE CASES OF SULFONAMIDES AND β-CYCLODEXTRIN COMPLEXES
- IMPROVEMENT OF ORAL BIOAVAILABILITY OF PREDNISOLONE BY β-CYCLODEXTRIN COMPLEXATION IN HUMANS
- ENHANCED ORAL BIOAVAILABILITY OF ANTIINFRAMMATORY DRUG FLURBIPROFEN IN RABBITS BY TRI-O-METHYL-β-CYCLODEXTRIN COMPLEXATION
- IMPROVEMENTS OF SOME PHARMACEUTICAL CHARACTERISTICS OF VARIOUS STEROIDAL DRUGS BY CYCLODEXTRIN COMPLEXATION
- 3-Alkoxycarbonyl-2-oxazolones and Their Homopolymers as Highly Preservable Amino-Protecting Reagents. tert-Butoxycarbonylation and Benzyloxycarbonylation of Amino Groups
- o_2-cu^-ASCORBIC ACID : A NOVEL OXIDATION SYSTEM FOR THE HIGHLY SELECTIVE O-CEALKYLATION OF 2-ALKOXYPHENOLS
- REDUCTION IN THE LOCAL TISSUE TOXICITY OF CHLORPROMAZINE BY β-CYCLODEXTRIN COMPLEXATION
- Study of Interaction of Pranoprofen with Human Serum Albumin : Binding Properties of Enantiomers and Metabolite
- ENANTIOSELECTIVE ORAL BIOAVAILABILITY OF O-ISOVALERYL PROPRANOLOL AS A POTENTIAL PRODRUG OF PROPRANOLOL
- ヘム-チオレート酵素活性中心構造の特性探求と医薬化学への応用
- Interaction of Fluorescent Probe 7-Anilino-4-methylcoumarin-3-(p)-benzoic Acid with Egg Albumin
- ENHANCED BIOAVAILABILITY OF DIGOXIN BY γ-CYCLODEXTRIN COMPLEXATION
- REDUCTION IN THE LOCAL TOXICITY OF CHLORPROMACINE AND ITS PHOTOPRODUCTS BY CYCLODEXTRIN COMPLEXATION
- PROTECTIVE MECHANISM OF β-CYCLODEXIRIN FOR THE HEMOLYSIS INDUCED WITH PHENOTHIAZINE NEUROLEPTICS IN VITRO
- CYCLODEXTRIN-INDUCED HEMOLYSIS AND SHAPE CHANGES OF HUMAN ERYTHROCYTES IN VITRO
- PROTECTIVE EFFECTS OF CYCLODEXTRINS ON THE HEMOLYSIS INDUCED WITH TRANQUILIZING PHENOTHIAZINES
- PROTECTIVE EFFECTS OF CYCLODEXTRINS ON DRUG-INDUCED HEMOLYSIS IN VITRO
- Nanomolar Quantification and Identification of Various Nitrosothiols by High Performance Liquid Chromatography Coupled with Flow Reactors of Metals and Griess Reagent
- Enhanced Dissolution of Poorly Water-Soluble Drugs by Water-Soluble Gelatin
- THE ROLE OF SERUM PROTEIN BINDING IN THE INTESTINAL ABSORPTION OF DRUGS
- Opposite Effects of Metoclopramide and Propantheline on Intestinal Absorption of Imipramine in Rats
- INTERACTION OF WARFARIN WITH HUMAN SERUM ALBUMIN
- Effect of N-B Transition on the Microenvironment Surrounding ^Cys in Human Serum Albumin
- Activity coefficients of dimethyl-.BETA.-cyclodextrin in aqueous solutions.
- The structure of the cyclodextrin complex. XI. Crystal structure of hexakis-(2,3,6-tri-o-methyl)-.ALPHA.-cyclodextrin-p-iodoaniline monohydrate.
- The structure of the cyclodextrin complex. XIV. Crystal structure of hexakis(2,3,6-tri-O-methyl)-.ALPHA.-cyclodextrin-benzaldehyde (1:1) complex.
- The structure of the cyclodextrin complex. XVIII. Crystal structure of .BETA.-cyclodextrin-benzyl alcohol (1:1) complex pentahydrate.
- The structure of the cyclodextrin complex. XV. Crystal structure of hexakis(2,3,6-tri-O-methyl)-.ALPHA.-cyclodextrin-p-nitrophenol(1:1)complex monohydrate.
- The structure of the cyclodextrin complex. XIX Crystal structures of hexakis(2,3,6-tri-O-methyl)-.ALPHA.-cyclodextrin complexes with (S)- and (R)-mandelic acid. Chiral recognition through the induced-fit conformational change of the macrocyclic ring.
- The structure of the cyclodextrin complex. X. Crystal structure of .ALPHA.-cyclodextrin-benzaldehyde (1:1) complex hexahyderate.
- The structure of the cyclodextrin complex. XVI. Crystal structure of heptakis(2,3,6-tri-O-methyl)-.BETA.-cyclodextrin-p-iodophenol(1:1) complex tetrahydrate.