IMPROVEMENTS OF SOME PHARMACEUTICAL CHARACTERISTICS OF VARIOUS STEROIDAL DRUGS BY CYCLODEXTRIN COMPLEXATION
スポンサーリンク
概要
著者
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HIRAYAMA Fumitoshi
Faculty of Pharmaceutical Sciences, Sojo University
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UEKAMA Kaneto
Faculty of Pharmaceutical Sciences, Sojo University
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OTAGIRI MASAKI
Faculty of Pharmaceutical Science, Kumamoto University
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Hirayama Fumitoshi
Faculty Of Pharmaceutical Sciences Kumamoto University
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Hirayama Fumitoshi
Faculty Of Pharmaceutical Sciences Sojo University
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Otagiri M
Graduate School Of Pharmaceutical Sciences Kumamoto University
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Otagiri M
Kumamoto Univ. Kumamoto Jpn
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Uekama Kaneto
Faculty Of Pharmaceutical Sciences Kumamoto University
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UEMURA YUJI
Faculty of Pharmaceutical Sciences, Kumamoto University
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FUJINAGA TOSHIO
Faculty of Pharmaceutical Sciences, Kumamoto University
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Uemura Yuji
Faculty Of Pharmaceutical Sciences Kumamoto University
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Fujinaga Toshio
Faculty Of Pharmaceutical Sciences Kumamoto University
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Otagiri Masaki
Faculty Of Pharmaceutical Science Kumamoto University
関連論文
- Involvement of Lipid Rafts of Rabbit Red Blood Cells in Morphological Changes Induced by Methylated β-Cyclodextrins(Biopharmacy)
- Pseudorotaxane-Like Supramolecular Complex of Coenzyme Q10 with γ-Cyclodextrin Formed by Solubility Method
- Improved Stability of OPALMON^[○!R] Tablets under Humid Conditions IV : Effect of Polysaccharides and Disintegrants on the Stability and Dissolution Property of OPALMON^[○!R] Tablets
- Improvement of Dissolution Properties of a New Helicobacter pylori Eradicating Agent (TG44) by Inclusion Complexation with β-Cyclodextrin
- Improvement of Solubility and Oral Bioavailability of 2-(N-Cyanoimino)-5-{(E)-4-styrylbenzylidene}-4-oxothiazolidine (FPFS-410) with Antidiabetic and Lipid-Lowering Activities in Dogs by 2-Hydroxypropyl-β-cyclodextrin
- Preparation and Pharmaceutical Evaluation of Liposomes Entrapping Salicylic Acid/γ-Cyclodextrin Conjugate
- Enhancing Effects of Galactosylated Dendrimer/α-Cyclodextrin Conjugates on Gene Transfer Efficiency(Biopharmacy)
- Effects of Cyclodextrins on the Aggregation of Recombinant Human Growth Hormone (rhGH)
- A Moderate Interaction of Maltosyl-α-cyclodextrin with Caco-2 Cells in Comparison with the Parent Cyclodextrin
- Analysis of the Phase Solubility Diagram of a Phenacetin/Competitor/β-Cyclodextrin Ternary System, Involving Competitive Inclusion Complexation
- Hydrolysis Behavior of Prednisolone 21-Hemisuccinate/β-Cyclodextrin Amide Conjugate : Involvement of Intramolecular Catalysis of Amide Group in Drug Release
- Effects of Aging on Crystallization, Dissolution and Absorption Characteristics of Amorphous Tolbutamide-2-Hydroxypropyl-β-cyclodextrin Complex
- Inhibitory Effect of 2-Hydroxypropyl-β-cyclodextrin on the Foaming Generated by the Phosphodiester Compound of Vitamin C and E, EPC-K1
- Enhanced Absorption of Cyclosporin A be Complexation with Dimethyl-β-cyclodextrin in Bile Duct-Cannulated and -Noncannulated Rats
- シクロデキストリン polypseudorotaxane によるPEG化タンパク質持続放出システムの構築
- 抗ヒスタミン薬とシクロデキストリンの相互作用ならびに苦味軽減効果
- ジメチルアセチル-β-シクロデキストリンによるエンドトキシンショック抑制作用
- 薬物/シクロデキストリン結合体封入リポソームによる薬物の体内動態の制御
- 糖修飾デンドリマー/シクロデキストリン結合体を用いた細胞特異的遺伝子デリバリー
- ジメチル-β-シクロデキストリンによる薬物排出ポンプの機能阻害におけるCaveolaeの関与
- シクロデキストリン結合体を利用したケトプロフェンの経口持続性製剤の設計
- ジメチル-β-シクロデキストリンによるP-糖タンパク質の機能阻害におけるCaveolaeの関与
- 薬物/シクロデキストリン複合体封入リポソームの薬物送達システムへの応用
- シクロデキストリン誘導体によるマクロファージからのNO産生の抑制効果
- 遅延放出製剤の設計における薬物/シクロデキストリン結合体の有効利用
- 抗炎症薬ビフェニル酢酸の直腸投与における薬物担体としての水溶性β-シクロテキストリン誘導体の有効利用
- Varying Effects of Cyclodextrin Derivatives on Aggregation and Thermal Behavior of Insulin in Aqueous Solution
- Spectroscopic Characterization of the Inclusion Complex of a Luteinizing Hormone-Releasing Hormone Agonist, Buserelin Acetate, with Dimethyl-β-cyclodextriin
- Preparation of Hydrophilic Nanoparticles of C_ with High Resistance to Aggregation during Storage, using 2-Hydroxypropyl-β-cyclodextrin
- Polypseudorotaxane Formation of Randomly-Pegylated Insulin with Cyclodextrins: Slow Release and Resistance to Enzymatic Degradation
- Prominent Inhibitory Effect of 2-Hydroxybutyl-β-cyclodextrin on Solution-mediated Polymorphic Transition of Chlorpropamide
- Enzymatic Hydrolysis of the Horn and Hoof of Cow and Buffalo
- Transparent, Adhesive Film Formation of Per-O-valeryl-β-cyclodextrin
- INCLUSION COMPLEXATIONS OF FLURBIPROFEN WITH β-CYCLODEXTRIN AND TRI-O-METHYL-β-CYCLODEXTRIN
- Interaction Mode of Dicumarol and Its Derivatives with Human Serum Albumin, α_1-Acid Glycoprotein and Asialo α_1-Acid Glycoprotein
- Catalytic Properties for Naphthoquinones and Partial Primary Structure of Rabbit Heart Acetohexamide Reductase
- Carbonyl Reductase Purified from Rabbit Liver Is Not the Product of a Carbonyl Reductase Gene (RCBR5 or RCBR6) Cloned from the Rabbit Liver cDNA Library
- Characterization of Acetohexamide Reductases Purified from Rabbit Liver, Kidney, and Heart: Structural Requirements for Substrates and Inhibitors
- Purifiation and Catalytic Properties of a Novel Acetohexamide-Reducing Enzyme from Rabbit Heart
- Stereoselective Reduction of Acetohexamide in Cytosol of Rabbit Liver
- Stability of a Cisplatin-Chondroitin Sulfate A Complex in Plasma and Kidney in Terms of Protein Binding
- Sex-Dependent Pharmacokinetics and in Vitro Reductive Metabolism of Acetohexamide in Wistar-Imamichi Rats
- Individual Variation of Acetohexamide Reductase Activities in Liver Microsomes and Cytosol of Rats
- Possible Enhancing Mechanism of the Cutaneous Permeation of 4-Biphenylylacetic Acid by β-Cyclodextrin Derivatives in Hydrophilic Ointment
- COMBINED USE OF CYCLODEXTRIN DERIVATIVES AND PENETRATION ENHANCER HPE-101 IN TRANSDERMAL DELIVERY OF PROSTAGLANDIN E_1
- High-performance liquid chromatography with chemiluminescence detection of penbutolol and its hydroxylated metabolite in rat plasma
- 2-Hydroxypropylated Cyclodextrins as a Sustained-Release Carrier for Fragrance Materials
- Effects of Repeated Clarithromycin Administration on the Pharmacokinetic Properties of Pindolol in Rats
- Effects of α_1-Acid Glycoprotein on Erythrocyte Deformability and Membrane Stabilization(Biopharmacy)
- Characterization of Ligand Binding Sites on the α_1-Acid Glycoprotein in Humans, Bovines and Dogs
- EFFECT OF REPEATED ADMINISTRATION OF PYRIDINOLCARBAMATE ON THE RENAL EXCRETION OF SOME DRUGS IN RABBITS
- Characterization of a Binding Site of UCN-01,a Novel Anticancer Drug on α_1-Acid Glycoprotein
- Inclusion Complex of 3,9-Bis(N, N-dimethylcarbamoyloxy)-5H-benzofuro[3,2-c]quinoline-6-one (KCA-098) with Heptakis(2,6-di-O-methyl)-β-cyclodextrin : Interaction and Dissolution Properties
- Effect of Grinding with Hydroxypropyl Cellulose on the Dissolution and Particle Size of a Poorly Water-Soluble Drug
- Inhibitory Effects of Flavonoids on Rabbit Heart Carbonyl Reductase
- Inhibition of Rabbit Heart Carbonyl Reductase by Fatty Acids
- Purification and Catalytic Properties of a Tetrameric Carbony1 Reductase from Rabbit heart
- STUDIES ON BEFUNOLOL REDUCTASE FROM RABBIT LIVER
- In Vivo and in Vitro Binding of (-)-Hydroxyhexamide, a Major Metabolite of Acetohexamide, to Rabbit Serum
- Metabolic Reduction of Acetohexamide in Rat Kidney : Sex Difference and Effect of Streptozotocin-Induced Diabetes
- SEX DIFFERENCE OF ACETOHEXAMIDE REDUCTION IN RAT LIVER
- EFFECTS OF VARIOUS FACTORS ON METABOLIC REDUCTION OF ACETOHEXAMIDE
- REDUCTION OF ACETOHEXAMIDE BY RABBIT HEART CYTOSOL
- Effect of Phenylbutazone on Serum Protein Binding and Pharmacokinetic Behavior of Sulfadimethoxine in Rabbits, Dogs and Rats
- SPECIES DIFFERENCE IN PROTEIN BINDING DISPLACEMENT OF SULFADIMETHOXINE
- EFFECT OF PHENYLBUTAZONE ON SERUM PROTEIN BINDING OF SULFADIMETHOXINE IN DIFFERENT ANIMAL SPECIES
- ALLEVIATION OF CHLORPROMAZINE-PHOTOSENSITIZED CONTACT DERMATITIS BY β-CYCLODEXTRIN DERIVATIVES AND THEIR POSSIBLE MECHANISMS
- REDUCTION IN PHOTOTOXICITY OF DRUGS BY CYCLODEXTRIN COMPLEXATIONS AND ITS POSSIBLE MECHANISM
- MODEL ANALYSIS OF INTERFACIAL TRANSFER AND ABSORPTION BEHAVIOR OF DRUG FOLLOWING DISSOLUTION FROM COMPRESSED TABLET : IN THE CASES OF SULFONAMIDES AND β-CYCLODEXTRIN COMPLEXES
- IMPROVEMENT OF ORAL BIOAVAILABILITY OF PREDNISOLONE BY β-CYCLODEXTRIN COMPLEXATION IN HUMANS
- ENHANCED ORAL BIOAVAILABILITY OF ANTIINFRAMMATORY DRUG FLURBIPROFEN IN RABBITS BY TRI-O-METHYL-β-CYCLODEXTRIN COMPLEXATION
- IMPROVEMENTS OF SOME PHARMACEUTICAL CHARACTERISTICS OF VARIOUS STEROIDAL DRUGS BY CYCLODEXTRIN COMPLEXATION
- Pharmaceutical Evaluation of Hydroxyalkylated β-Cyclodextrin Derivatives
- REDUCTION IN THE LOCAL TISSUE TOXICITY OF CHLORPROMAZINE BY β-CYCLODEXTRIN COMPLEXATION
- Study of Interaction of Pranoprofen with Human Serum Albumin : Binding Properties of Enantiomers and Metabolite
- ENANTIOSELECTIVE ORAL BIOAVAILABILITY OF O-ISOVALERYL PROPRANOLOL AS A POTENTIAL PRODRUG OF PROPRANOLOL
- Interaction of Fluorescent Probe 7-Anilino-4-methylcoumarin-3-(p)-benzoic Acid with Egg Albumin
- ENHANCED BIOAVAILABILITY OF DIGOXIN BY γ-CYCLODEXTRIN COMPLEXATION
- Potential Use of 2-Hydroxypropyl-β-cyclodextrin for Preparation of Orally Disintegrating Tablets Containing dl-α-Tocopheryl Acetate, an Oily Drug
- Preparation of Four Types of Coenzyme Q10/γ-Cyclodextrin Supramolecular Complexes and Comparison of Their Pharmaceutical Properties
- REDUCTION IN THE LOCAL TOXICITY OF CHLORPROMACINE AND ITS PHOTOPRODUCTS BY CYCLODEXTRIN COMPLEXATION
- PROTECTIVE MECHANISM OF β-CYCLODEXIRIN FOR THE HEMOLYSIS INDUCED WITH PHENOTHIAZINE NEUROLEPTICS IN VITRO
- CYCLODEXTRIN-INDUCED HEMOLYSIS AND SHAPE CHANGES OF HUMAN ERYTHROCYTES IN VITRO
- PROTECTIVE EFFECTS OF CYCLODEXTRINS ON THE HEMOLYSIS INDUCED WITH TRANQUILIZING PHENOTHIAZINES
- PROTECTIVE EFFECTS OF CYCLODEXTRINS ON DRUG-INDUCED HEMOLYSIS IN VITRO
- EFFECTS OF CYCLODEXTRINS ON THE PHOTOLYSES OF TRAN-QUILIZING PHENOTHIAZINES IN AQUEOUS SOLUTION
- Nanomolar Quantification and Identification of Various Nitrosothiols by High Performance Liquid Chromatography Coupled with Flow Reactors of Metals and Griess Reagent
- Enhanced Dissolution of Poorly Water-Soluble Drugs by Water-Soluble Gelatin
- THE ROLE OF SERUM PROTEIN BINDING IN THE INTESTINAL ABSORPTION OF DRUGS
- MODEL ANALYSES OF INTERFACIAL TRANSFER AND ABSORPTION BEHAVIORS OF DRUGS FOLLOWING DISSOLUTION : APPROACH TO EVALUATION PROCEDURE OF BIOAVAILABILITY
- IMPROVEMENT OF CHEMICAL STABILITY OF PROSTAGLANDINS BY INCLUSION COMPLEXATION WITH METHYLATED CYCLODEXTRINS AND THEIR STABILIZATION MECHANISM
- The structure of the cyclodextrin complex. XI. Crystal structure of hexakis-(2,3,6-tri-o-methyl)-.ALPHA.-cyclodextrin-p-iodoaniline monohydrate.
- The structure of the cyclodextrin complex. XIV. Crystal structure of hexakis(2,3,6-tri-O-methyl)-.ALPHA.-cyclodextrin-benzaldehyde (1:1) complex.
- Micellar effects on base-catalyzed isomerization of prostaglandin A1 and prostaglandin A2.
- The structure of the cyclodextrin complex. XVIII. Crystal structure of .BETA.-cyclodextrin-benzyl alcohol (1:1) complex pentahydrate.
- The structure of the cyclodextrin complex. XV. Crystal structure of hexakis(2,3,6-tri-O-methyl)-.ALPHA.-cyclodextrin-p-nitrophenol(1:1)complex monohydrate.
- The structure of the cyclodextrin complex. XIX Crystal structures of hexakis(2,3,6-tri-O-methyl)-.ALPHA.-cyclodextrin complexes with (S)- and (R)-mandelic acid. Chiral recognition through the induced-fit conformational change of the macrocyclic ring.
- The structure of the cyclodextrin complex. X. Crystal structure of .ALPHA.-cyclodextrin-benzaldehyde (1:1) complex hexahyderate.
- The structure of the cyclodextrin complex. XVI. Crystal structure of heptakis(2,3,6-tri-O-methyl)-.BETA.-cyclodextrin-p-iodophenol(1:1) complex tetrahydrate.