Synthesis of Condensed Quinoxalines. II. A New Synthesis of Pyrrolo- [2,3-b] quinoxalines
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概要
- 論文の詳細を見る
The reaction of ethyl 2- (3-chloro-2-quinoxalinyl) -2-cyanoacetate (I) with various amines : ammonia, methylamine, ethanolamine, γ-dimethylaminopropylamine, benzylamine, and p-phenetidine, gave the corresponding 1-substituted ethyl 2-aminopyrrolo [2,3-b] quinoxaline-3-carboxylates (IIIa-f) at about 80-90% yield. The similar reaction of α- (3-chloro-2-quinoxalinyl) -malondinitrile (II) with various primary amines was carried out to give the corresponding 1-substituted 2-aminopyrrolo [2,3-b] quinoxaline-3-carbonitriles (VIIa-d) at 86-94% yield (Table I).
- 公益社団法人日本薬学会の論文
- 1970-10-25
著者
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高橋 浩
Faculty Of Pharmaceutical Science Hoshi University
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乙益 寛隆
Hoshi College of Pharmacy
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高橋 浩
Hoshi Institute of Pharmaceutical Sciences
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大宮 茂
Hoshi College of Pharmacy
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大宮 茂
星薬科大学
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関口 敏江
Hoshi College of Pharmacy
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