Reaction of Aromatic Heterocyclic Nitro Compounds with Potassium Cyanide. III. Some Nitroquinoline 1-Oxides
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概要
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The reaction of 3-nitroquinoline 1-oxide with potassium cyanide in methanol was carried out producing 3-methoxycinchoninonitrile 1-oxide (I) and 3-methoxy-1H-pyrazolo [4,3-b] quinoline-9-carboxamide (II). 5-Nitroquinoline 1-oxide gave 5-methoxyquinoline-6-carbonitrile 1-oxide (XIII) and 7-aminoisoxazolo [3,4-f] quinoline 1-oxide (XIV), whereas 6-nitroquinoline 1-oxide gave methyl 5-cyano-6-methoxyquinaldimidate 1-oxide (VI), 5-cyano-6-methoxyquinaldamide 1-oxide (VII), and 1-hydroxy-6-nitrocarbostyril (VIII) by the similar type reactions. 4-Nitroquinoline 1-oxide produced 4-methoxyquinoline 1-oxide.
- 公益社団法人日本薬学会の論文
- 1971-09-25
著者
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高橋 浩
Faculty Of Pharmaceutical Science Hoshi University
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岡本 敏彦
Faculty Of Pharmaceutical Sciences University Of Tokyo
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岡本 敏彦
Sato Pharmaceutical Co. Ltd.
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高橋 浩
Hoshi Institute of Pharmaceutical Sciences
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