Reaction of Aromatic Heterocyclic Nitro Compound with Potassium Cyanide. I. 3-Nitroquinoline
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概要
- 論文の詳細を見る
3-Nitroquinoline was reacted with potassium cyanide in methanol at refluxing temperature to give 3-methoxycinchoninonitrile (I) and 1-aminoisoxazolo [3,4-c] quinoline (II) in the yield of 62% and 30%, respectively. 3-Nitrocinchoninonitrile (III), which was prepared by the reaction of 3-nitroquinoline with potassium cyanide in the presence of potassium ferricyanide, was treated with potassium cyanide in methanol to from I, and III was converted into II by reduction with zinc dust and ammonium chloride.
- 公益社団法人日本薬学会の論文
- 1968-09-25
著者
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高橋 浩
Faculty Of Pharmaceutical Science Hoshi University
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岡本 敏彦
Faculty Of Pharmaceutical Sciences University Of Tokyo
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岡本 敏彦
Sato Pharmaceutical Co. Ltd.
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高橋 浩
Hoshi Institute of Pharmaceutical Sciences
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