Study of the Interactions between Sulfamethizole and Three Anti-inflammatory Propionic Acid Derivatives at the Renal Level in Rats
スポンサーリンク
概要
- 論文の詳細を見る
The effects of three anti-inflammatory propionic acid derivatives (ketoprofen, fenbufen and flurbiprofen) on renal excretion of sulfamethizole were investigated in rats, in order to clarify the mechanisms involved. The clearance ratio of sulfamethizole was markedly decreased after ketoprofen or fenbufen infusion, while flurbiprofen had no effect on sulfamethizole excretion. From these results, it is speculated that the decrease of renal excretion of sulfamethizole caused by ketoprofen or fenbufen is mainly due to competitive interaction between sulfamethizole and ketoprofen or fenbufen at the renal secretory level.
- 社団法人日本薬学会の論文
- 1985-11-25
著者
-
高田 昌彦
Faculty Of Pharmaceutical Sciences Health Sciences University Of Hokkaido
-
宮崎 正三
Faculty of Pharmaceutical Sciences, Health Science University of Hokkaido
-
千葉 一基
北海道医療大学薬学部
-
千葉 一基
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
-
菊地 敏
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
-
西村 成勲
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
-
樋口 尚代
Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University
-
高田 昌彦
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
-
高田 昌彦
北海道医療大 薬
-
菊地 敏
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
-
樋口 尚代
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
-
西村 成勲
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
-
高田 昌彦
Faculty Of Pharmaceutical Sciences Higashi-nippon Gakuen University
-
宮崎 正三
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
関連論文
- 乾燥水酸化アルミニウムゲル・水酸化マグネシウム懸濁内服用顆粒併用時のオメプラゾール血中濃度の低下
- 29-P3-50 大学院薬学臨地実習を介した医療機関との共同研究の推進(薬学教育,社会の期待に応える医療薬学を)
- P-499 大学院薬学臨地実習を介した医療現場との共同研究の展開
- ラットにおける塩酸バンコマイシンの難吸収に関与する要因の検討
- ラットにおけるジソピラミドの腎排泄(第1報)
- 塩酸グラニセトロンの体液中濃度測定法と体内動態
- B-18 MRSA 感染症患者の TDM
- 塩酸ピロカルピン固体分散体製剤の唾液分泌効果
- 副交感神経様作用薬物の唾液分泌促進に関する研究
- キトサンおよびアルギン酸ナトリウムを用いた塩酸ジルチアゼムの口腔粘膜付着性フィルム剤
- 口腔乾燥症の軽減を目的とした塩酸ピロカルピン固体分散体製剤の調製とその評価
- 培養腎上皮細胞LLC-PK_1におけるエノキサシンの輸送
- Na^+-and Energy-Dependent Transport of Cadmium into LLC-PK_1 Cells
- Thermally Gelling Poloxamine Synperonic T908 Solution as a Vehicle for Rectal Drug Delivery
- ラット腎皮質におけるナリジクス酸及びエノキサシンの取り込み
- Biliary Excretion of Furosemide Glucuronide in Rabbits
- Transport Mechanisms of Enoxacin in Rat Brush-Border Membrane of Renal Cortex : Interaction with Organic Cation Transport System and Ionic Diffusion Potential Dependent Uptake
- プルロニックF-127の経皮吸収ゲル基剤としての有用性
- パラアミノサリチル酸ナトリウムによるリファンピシンのヒト直腸吸収の増加
- Chitosan and Sodium Alginate Based Bioadhesive Tablets for Intraoral Drug Delivery
- Sustained Release of Phenytoin Following the Oral Administration of Phenytoin Sodium : Ethylcellulose Microcapsules in Human Subjects and Rabbits
- Urinary Levels of γ-Carboxyglutamic Acid and Its Clinical Significance
- Bioavailability and Diuretic Effect of Bumetanide Following Rectal Administration of Suppositories Containing Weak Acids in Human Subjects
- Enhanced Absorption of Bumetanide from Suppositories Containing Weak Acids in Rabbits
- External Control of Drug Release and Penetration. VI. Enhancing Effect of Ultrasound on the Transdermal Absorption of Indomethacin from an Ointment in Rats
- Antitumor Effect of Pluronic F-127 Gel Containing Mitomycin C on Sarcoma-180 Ascites Tumor in Mice
- Protein Binding of Sulfonamides and Displacing Effects of Sulfinpyrazone on the Bound Sulfonamides in Nephrotic Patients in the Remissive Stage
- Transformation and Excretion of Drugs in Biological Systems. IX. Interactions between Sulfinpyrazone and Sulfonamides, and between Oxyphenbutazone and Sulfonamides in Dogs
- Transformation and Excretion of Drugs in Biological Systems. VIII. Interactions between 5-n-Butyl-1-cyclohexyl-2,4,6-trioxoperhydro-pyrimidine and Sulfonamides in Dogs
- Transformation and Excretion of Drugs in Biological Systems. VII. Effect of Biotransformation on Renal Excretion of Sulfonamides
- Transformation and Excretion of Drugs in Biological Systems. VI. Correlation between Renal Excretion and Biotransformation of Sulfisomidine and Sulfamethizole
- Transformation and Excretion of Drugs in Biological Systems. V. Correlation between Renal Excretion and Biotransformation of Sulfadimethoxine
- Studies on Metabolism of 2-Methyl-3-o-tolyl-4(3H)-quinazolinone. II. Physiological Disposition and Metabolic Fate of 2-Methyl-3-o-tolyl-4 (3H)-quinazolinone.
- Studies on Metabolism of 2-Methyl-3-o-tolyl-4 (3H)-quinazolinone. I. The Estimation of 2-Methyl-3-o-tolyl-4 (3H)-quinazolinone in Biological Materials.
- Comparative Study of the Interaction between Sulfamethizole and Ibufenac, Sulindac or Mepirizole at the Renal Level in Rats(Pharmaceutical,Chemical)
- Study of the Interactions between Sulfamethizole and Alclofenac, Diclofenac or Tiaprofenic Acid in Rats(Pharmaceutical)
- Comparative Study of Interactions between 4-Biphenylacetic Acid and Sulfamethizole, and between Fenbufen and Sulfamethizole in Rats
- Study of the Interactions between Sulfamethizole and Three Anti-inflammatory Propionic Acid Derivatives at the Renal Level in Rats
- Studies on the Photolysis and Hydrolysis of Furosemide in Aqueous Solution
- ウサギにおけるセフメタゾール坐剤の直腸吸収に及ぼすデカン酸/α-シクロデキストリン包接化合物の影響
- Dissolution Behavior of Prednisolone from Solid Dispersion Systems with Cyclodextrins and Polyvinylpyrrolidone
- Fibrinogen Microspheres as Novel Drug Delivery Systems for Antitumor Drugs
- Biochemical and Biophysical Behavior of Plasma Albumin. III. Effects of Several Uremic Toxins on Normal Plasma Albumin
- Pluronic F-127 Gels as a NOvel Vehicle for Rectal Administration of Indomethacin
- Preparation and Evaluation in Vitro and in Vivo of Fibrinogen Micropheres Containing Adrinamycin
- Antitumor Effect of Fibrinogen Microparticles Containing Adriamycin on Ehrlich Ascites Carcinoma in Mice
- Antitumor Effect of Implanted Ethylene-Vinyl Alcohol Copolymer Matrices Containing Anticancer Agents on Ehrlich Ascites Carcinoma and P388 Leukemia in Mice
- Interaction of Drugs with Bile Components. II. Effect of Bile on the Absorption of Indomethacin and Phenylbutazone in Rats
- Effect of Antacids on the Dissolution Behavior of Tetracycline and Methacycline
- Interaction of Drugs with Bile Components. I. Effects of Bile Salts on the Dissolution Behavior of Indomethacin and Phenylbutazone
- Common Ion Effect of Chloride on the Dissolution Properties of Papaverine Hydrochloride
- The Use of Chitin and Chitosan as Drug Carriers
- Controlled Release of Prednisolone from Ethylene-Vinyl Acetate Copolymer Matrix
- Dissolution Properties of Salt Forms of Berberine
- Use of Fibrin Film as a Carrier for Drug Delivery : In Vitro Drug Permeabilities of Fibrin Film
- Sustained Release of Indomethacin from Chitosan Granules
- ジソピラミド製剤の溶出並びにバイオアベイラビリティの評価
- Study of Interactions between Ibuprofen and Sulfonamides, and between Bucolome and Sulfonamides in Rats
- Effect of Additives on the Polymorphic Transformation of Chlortetracycline Hydrochloride Crystals
- Polymorphic Transformation of Chlortetracycline Hydrochloride Crystals Studied by Infrared Spectrophotometric Method
- A Comparison of Solubility Characteristics of Free Bases and Hydrochloride Salts of Tetracycline Antibiotics in Hydrochloric Acid Solutions
- Effect of Crystal Forms on the Dissolution Behavior and Bioavailability of Tetracycline, Chlortetracycline, and Oxytetracycline Bases
- Preparation of Solid dispersion Systems of Disopyramide with Polyvinylpyrrolidone and γ-Cyclodextrin
- Further Investigation on the Interaction of Sulfonamides with Non-steroidal Anti-inflammatory Agents in Dogs
- Pharmacokinetic Aspects of the Interaction of Sulfonamides with Ibuprofen or Mepirizole in Dogs
- Dissolution Behavior and Gastrointestinal Absorption of Sulfamethoxazole from Sulfamethoxazole-Polyvinylpyrrolidone Coprecipitates
- Fundamental Pharmacokinetic Behavior of Sulfadimethoxine, Sulfamethoxazole and Their Biotransformed Products in Dogs
- Dissolution Behavior and Gastrointestinal Absorption of Dicumarol from Solid Dispersion Systems of Dicmarol-Polyvinylpyrrolidone and Dicumarol-β-Cyclodextrin
- Influence of Dietary Components on the Bioavailability of Phenytoin
- Sustained-Release and Intragastric-Floating Granules of Indomethacin Using Chitosan in Rabbits
- Controlled Release of Pilocarpine Hydrochloride from Ethylene-Vinyl Alcohol Copolymer Matrices
- CONTROLLED DRUG RELEASE BY ULTRASOUND IRRADIATION
- External Control of Drug Release. IV. : Controlled Release of 5-Fluorouracil from a Hydrophilic Polymer Matrix by Microwave Irradiation
- Sustained Release of Insulin from a Hydrophilic Polymer Matrix Implanted in Diabetic Rats
- Effect of Pluronic Gels on the Rectal Absorption of Indomethacin in Rabbits(Pharmaceutical)
- Pluronic F-127 Gels as a Vehicle for Topical Administration of Anticancer Agents
- Factors Affecting the Release Patterns of 5-Fluorouracil from Ethylene-Vinyl Acetate Copolymer Matrices
- Controlled Release of 5-Fluorouracil from Hydrophilic Ethylene-Vinyl Alcohol Copolymer Matrices
- Antitumor Effect of Ethylene-Vinyl Acetate Copolymer Matrices containing 5-Fluorouracil on Ehrlich Ascites Carcinoma in Mice
- Use of Fibrin Film as a Carrier for Drug Delivery : A Long-acting Delivery System for Pilocarpine into the Eye
- A Comparison of Bioavailability of Free Bases and Hydrochloride Salts of Chlortetracycline, Demethylchlortetracycline, and Methacycline
- Basic Studies on Controlled Transdermal Delivery on Nicardipine Hydrochloride Using Ethylene-Vinyl Acetate and Ethylene-Vinyl Alcohol Copolymer Membranes
- キトサンの医薬品製剤への有効利用 : キトサン・アルギン酸を用いた口腔粘膜付着性製剤