Use of Fibrin Film as a Carrier for Drug Delivery : A Long-acting Delivery System for Pilocarpine into the Eye
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概要
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Fibrin film was evaluated as a new carrier for a long-acting delivery system for pilocarpine. The release characteristics of the pilocarpine-fibrin film system were investigated in in vitro and in vivo test models. The results indicated that the use of the pilocarpinefibrin film system is more effective than that of the conventional liquid dosage form for prolonging the duration of a desirable pupillary response. Its good biocompatibility, flexibility, and heat processability suggest the material to be a good candidate system for pilocarpine delivery into the eye.
- 1982-09-25
著者
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宮崎 正三
北海道医療大学薬学部
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高田 昌彦
Faculty Of Pharmaceutical Sciences Health Sciences University Of Hokkaido
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宮崎 正三
Faculty of Pharmaceutical Sciences, Health Science University of Hokkaido
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高田 昌彦
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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石井 邦明
Faculty of Pharmaceutical Sciences, Josai University
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石井 邦明
Faculty Of Pharmaceutical Sciences Josai University:(present Address)taisho Pharmaceutical Co.
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宮崎 正三
Faculty Of Pharmaceutical Sciences Higashi-nippon-gakuen University
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