Chemical Studies of Chinese Licorice-Roots. II. Five New Flavonoid Constituents from the Roots of Glycyrrhiza aspera PALL. Collected in Xinjiang

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概要

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• From the air-dried roots of Glycyrrhiza aspera PALL. (Leguminosae) collected in Xinjiang province, China (known as a kind of "Shinkyo-Kanzo"), five new flavonoid compounds named glucoisoliquiritin apioside (1) (a chalcone bisdesmosidic triglycoside), 7-O-apioglucosyl-7,4'-dihydroxyflavone (5) (a flavone diglycoside), dehydroglyasperin C (7) (a prenylated isoflav-3-ene derivative), asperopterocarpin (9) and 1-methoxyphaseollidin (12) (an O-prenylpterocarpan and a C-prenylpterocarpan, respectively), were isolated together with four known saponins, one known flavonoid O-glycoside, two known flavonoid C-glycosides, and seven flavonoids. The structures of the new compounds have been elucidated on the basis of their chemical and physicochemical properties. Some pterocarpan compounds showed moderate cytotoxic activity against KB and L1210 cells.

• 公益社団法人日本薬学会の論文
• 1998-10-15

著者

• Hiwatashi Kazuyuki

  秋田県農林水産技術センター総合食品研究所

• 北川 勲

  大阪大学

• 北川 勲

  大阪大学薬学部生薬学教室

• Kitagawa Isao

  Graduate School Of Pharmaceutical Sciences Osaka Univ.

• Kitagawa Isao

  Faculty Of Pharmaceutical Sciences Osaka University:(present Address)kinki University

• KOBAYASHI Motomasa

  Faculty of Pharmaceutical Sciences, Osaka University

• Kobayashi M

  Fujisawa Pharmaceutical Co. Ltd. :(peresent Address)fujisawa Research Insitute Of America Inc. North

• Kobayashi M

  Faculty Of Pharmaceutical Sciences Osaka University

• Kobayashi Motomasa

  Faculty Of Pharmaceutical Sciences

• Kobayashi Masao

  Pharmaceutical Research Laboratory Tanabe Seiyaku Co. Ltd.

• Kobayashi M

  Graduate School Of Pharmaceutical Sciences Osaka University

• HORI Kazuyuki

  Faculty of Pharmaceutical Sciences, Osaka University

• CHEN Wei-Zhong

  Faculty of Pharmaceutical Sciences, Osaka University

• REN Jiali

  Xinjiang Institute of Chemistry, Academia Sinca

• Ren J

  中国科学院

• Hori K

  Kao Co. Ltd. Tochigi Jpn

• Hori Kazuyuki

  The Central Research Laboratory Hitachi Ltd.

• Kitagawa Isao

  Faculty Of Pharmaceutical Sciences

• 小林 資正

  Graduate School Of Pharmaceutical Sciences Osaka University

• Kojima Hiroaki

  R&d Co. Kobayashi Pharmaceutical Co. Ltd.

• Chen Wei-zhong

  Faculty Of Pharmaceutical Sciences Osaka University

• Ren Jiali

  Xinjiang Institute Of Chemistry Academia Sinca

• Hata K

  Akita Research Institute Of Food And Brewing

• Kawaguchi M

  Graduate School Of Pharmaceutical Sciences Osaka University

• Kojima Hiroaki

  Kobayashi Pharmaceutical Co. Ltd. R&d Company

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