Novel Neuronal Nitric Oxide Synthase(nNOS)Selective Inhibitor, Aplysinopsin-Type Indole Alkaloid, from Marine Sponge Hyrtios erecta
スポンサーリンク
概要
- 論文の詳細を見る
Two novel aplysinopsin-type indole alkaloids, 1 and 2, and three known indole alkaloids were isolated from the marine sponge Hyrtios erecta. These compounds exhibited selective inhibitory activity against the neuronal isozyme of nitric oxide synthase(nNOS). Furthermore, new quinolone 7 was also isolated from the same marine sponge. The chemical structures of these new compounds were elucidated on the basis of spectroscopic analysis.
- 公益社団法人日本薬学会の論文
- 2001-10-01
著者
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Akiyama Shin-ichi
大阪大学 薬研究
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北川 勲
大阪大学
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Akiyama Shin-ichi
The Institute Of Chemotherapy Kagoshima University Faculty Of Medicine
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AOKI Shunji
Graduate School of Pharmaceutical Sciences, Osaka University
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KOBAYASHI Motomasa
Graduate School of Pharmaceutical Sciences, Osaka University
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Aoki S
Graduate School Of Pharmaceutical Sciences Osaka University
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Aoki Shunji
Graduate School Of Pharmaceutical Sciences Osaka University
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北川 勲
大阪大学薬学部生薬学教室
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Kitagawa Isao
Graduate School Of Pharmaceutical Sciences Osaka Univ.
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Kitagawa Isao
Faculty Of Pharmaceutical Sciences Osaka University:(present Address)kinki University
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Kobayashi M
Fujisawa Pharmaceutical Co. Ltd. :(peresent Address)fujisawa Research Insitute Of America Inc. North
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TAKASHIMA Akira
Aburahi Laboratories, Shionogi Research Laboratories, Shionogi & Co., Ltd
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TANAKA Yoshimi
Aburahi Laboratories, Shionogi & Co., Ltd.
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Aoki Shinji
Research Laboratory Taisho Pharmaceutical Co. Ltd.
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Kobayashi M
Faculty Of Pharmaceutical Sciences Osaka University
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Kobayashi Masao
Pharmaceutical Research Laboratory Tanabe Seiyaku Co. Ltd.
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Kobayashi M
Graduate School Of Pharmaceutical Sciences Osaka University
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Tanaka Yoshimi
Aburahi Laboratories Shionogi & Co. Ltd.
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Tanaka Yoshimi
Aburahi Laboratories Shionogi And Co. Ltd.
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YE Ying
Graduate School of Pharmaceutical Sciences, Osaka University
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HIGUCHI Kouichi
Graduate School of Pharmaceutical Sciences, Osaka University
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Ye Ying
Graduate School Of Pharmaceutical Sciences Osaka University
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Higuchi K
Graduate School Of Pharmaceutical Sciences Osaka University
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Kitagawa Isao
Faculty Of Pharmaceutical Sciences
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Takashima A
Aburahi Laboratories Shionogi And Co. Ltd.
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Takashima Akira
Aburahi Laboratories Shionogi & Co. Ltd.
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小林 資正
Graduate School Of Pharmaceutical Sciences Osaka University
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Kobayashi Motomasa
Graduate School Of Pharmaceutical Sciences Osaka Univ.
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Kawaguchi M
Graduate School Of Pharmaceutical Sciences Osaka University
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Aoki Shunji
Graduate School Of Industrial Engineering Tokai University
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