Bastadins, cyclic tetramers of brominated-tyrosine derivatives, selectively inhibit the proliferation of endothelial cells

スポンサーリンク

概要

• 論文の詳細を見る
• Japanese Society of Pharmacognosyの論文
• 2006-08-20

著者

• Akiyama Shin-ichi

  Department Of Molecular Oncology Graduate School Of Medical And Dental Sciences Kagoshima University

• Akiyama Shin-ichi

  大阪大学 薬研究

• Akiyama Shin-ichi

  The Institute Of Chemotherapy Kagoshima University Faculty Of Medicine

• AOKI Shunji

  Graduate School of Pharmaceutical Sciences, Osaka University

• KOBAYASHI Motomasa

  Graduate School of Pharmaceutical Sciences, Osaka University

• KOTOKU Naoyuki

  Graduate School of Pharmaceutical Sciences, Osaka University

• Aoki S

  Graduate School Of Pharmaceutical Sciences Osaka University

• Aoki Shunji

  Graduate School Of Pharmaceutical Sciences Osaka University

• CHO Seok-hwan

  Graduate School of Pharmaceutical Sciences, Osaka University

• HIRAMATSU Atsushi

  Graduate School of Pharmaceutical Sciences, Osaka University

• Cho Seok-hwan

  Graduate School Of Pharmaceutical Sciences Osaka University

• Kobayashi M

  Fujisawa Pharmaceutical Co. Ltd. :(peresent Address)fujisawa Research Insitute Of America Inc. North

• Aoki Shinji

  Research Laboratory Taisho Pharmaceutical Co. Ltd.

• Kobayashi M

  Faculty Of Pharmaceutical Sciences Osaka University

• Kobayashi Masao

  Pharmaceutical Research Laboratory Tanabe Seiyaku Co. Ltd.

• Kotoku Naoyuki

  Graduate School Of Pharmaceutical Sciences Osaka University

• 小林 資正

  Graduate School Of Pharmaceutical Sciences Osaka University

• Kobayashi Motomasa

  Graduate School Of Pharmaceutical Sciences Osaka Univ.

• Kawaguchi M

  Graduate School Of Pharmaceutical Sciences Osaka University

• Hiramatsu Atsushi

  Graduate School Of Pharmaceutical Sciences Osaka University

• Aoki Shunji

  Graduate School Of Industrial Engineering Tokai University

関連論文

• Structures of Echinoside A and B, Two Antifungal Oligoglycosides from the Sea Cucumber Actinopyga echinites (JAEGER)
• 海綿由来のトリデカペプチドラクトンであるテオネラペプトライドIeが誘発する表層アクチンの撹乱によって引き起こされるヒトデ未成熟卵の形態異常
• Marine Natural Products. XXIV. : The Absolute Stereostructure of Misakinolide A, a Potent Cytotoxic Dimeric Macrolide from an Okinawan Marine Sponge Theonella sp.
• Marine Natural Products. XXIII. : Three New Cytotoxic Dimeric Macrolides, Swinholides B and C and Isoswinholide A, Congeners of Swinholide A, from the Okinawan Marine Sponge Theonella swinhoei
• 17 Theonella属海綿の産生する二量体マクロリド類の化学構造と抗腫瘍活性(口頭発表の部)
• Marine Natural Products. XXII. : The Absolute Stereostructure of Swinholide A, a Potent Cytotoxic Dimeric Macrolide from the Okinawan Marine Sponge Theonella swinhoei
• An Immunohistochemical Analysis of Gastric B-cell Lymphomas : Stromal Cells Exhibit Peculiar Histogenesis in Gastric B-cell Lymphomas
• 19 沖縄産Theonella属 海綿2種の産生するアミノセスキテルペン類および生物活性ペプチドラクトン類の化学構造
• STRUCTURE OF THEONELLAPEPTOLIDE ID, A NEW BIOACTIVE PEPTOLIDE FROM AN OKIKAWAN MARINE SPONGE, THEONELLA SP. (THEONELLIAE)
• Marine Natural Products. XXXII. Absolute Configurations of C-4 of the Manoalide Family, Biologically Active Sesterterpenes from the Marine Sponge Hyrtions erecta
• Marine Natural Products. XXXI. Structure-Activity Correlation of a Potent Cytotoxic Dimeric Macrolide Swinholide A, from the Okinawan Marine Sponge Theonella swinhoei, and Its Isomers
• インドネシア薬用植物 第XI報 : Caesalpinia major(マメ科)根から単離した2種の新規カッサン型フラノジテルペンcaesaldekarin a及びbの化学構造(発表論文抄録(1994))
• Indonesian Medicinal Plants. XI. Chemical Structures of Caesaldekarins a and b, Two New Cassane-Type Furanoditerpenes from the Roots of Caesalpinia major (Fabaceae)
• The Small Heat Shock Protein αB-Crystallin Inhibits Differentiation-Induced Caspase 3 Activation and Myogenic Differentiation(Molecular and Cell Biology)
• A Functional Role of Intracellular Loops of Human Multidrug Resistance Protein 1
• P-54 ANALYSIS OF MOLECULAR MECHANISM OF MRP1 BY AGOSTEROL A, A MDR REVERSING SPONGEAN STEROL
• The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression
• Reversal of the resistance to STI571 in human chronic myelogenous leukemia K562 cells
• Lembehsterols A and B, Novel Sulfated Sterols Inhibiting Thymidine Phosphorylase, from the Marine Sponge Petrosia strongylata
• Reversal of P-Glycoprotein and Multidrug-Resistance Protein-Mediated Drug Resistance in KB Cells by 5-0-Benzoylated Taxinine K.
• The expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor is correlated to angiogenesis in breast cancer
• Expression of Thymidine Phosphorylase in Human Gastric Carcinoma
• Asymmetric Synthesis by the Intramolecular Haloetherification Reaction of Ene Acetal : Discrimination of Prochiral Dienes in Cyclohexane Systems
• 海洋天然物研究(30) : 沖縄産海綿Theonella swinhoeiより得られた2種の新規3-ケト-4-メチレンステロイド,テオネラステロンおよびコニカステロンと,ディールス-アルダー型の二量体ステロイド,ビステオネラステロン(発表論文抄録(1991年))
• 海洋天然物研究(29) : 渦鞭毛藻Heterosigma akashiwoより得られたω3型不飽和脂肪酸を構成脂肪酸とする4種の糖脂質,ヘテロシグマグリコリピド I, II, IIIおよびIV(発表論文抄録(1991年))
• Marine Natural Products. XXX. Two New 3-Keto-4-methylene Steroids, Theonellasterone and Conicasterone, and a Diels-Alder Type Dimeric Steroid Bistheonellasterone, from the Okinawan Marine Sponge Theonella swinhoei
• Marine Natural Products. XXIX. Heterosigma-glycolipids I, II, III, and IV, Four Diacylglyceroglycolipids Possessing ω3-Polyunsaturated Fatty Acid Residues, from the Raphidopycean Dinoflagellate Heterosigma akashiwo
• 44 海綿由来のキノリチジンアルカロイド大環状二量体の化学構造と光学活性(口頭発表の部)
• ARAGUSPONGINES B, C, D, E, F, G, H, AND J, NEW VASODILATIVE BIS-1-OXAQUINOLIZIDINE ALKALOIDS FROM AN OKINAWAN MARINE SPONGE, XESTOSPONGIA SP.
• 14 海綿Dysidea arenaria由来の新規抗腫瘍性デプシペプチドArenastatin A(口頭発表の部)
• Marine Natural Products. X. Pharmacologically Active Glycolipids from the Okinawan Marine Sponge Phyllospongia foliascens (PALLAS)
• Foliaspongin, an Antiinflammatory Bishomosesterterpene from the Marine Sponge Phyllospongia foliascens (PALLAS)
• Bastadins, cyclic tetramers of brominated-tyrosine derivatives, selectively inhibit the proliferation of endothelial cells
• P-226 NOVEL POLYKETIDES, SHIMALACTONES A AND B, FROM A MARINE-DERIVED FUNGUS EMERICELLA VARIECOLOR GF10
• P-98 CORTISTATINS A, B, C, AND D, ANTI-ANGIOGENIC STEROIDAL ALKALOIDS, FROM THE MARINE SPONGE CORTICIUM SIMPLEX
• P-63 SYNTHETIC STUDIES OF BASTADIN 6, AN ANTI-ANGIOGENIC SUBSTANCE FROM MARINE SPONGE
• Sesquiterpene Aminoquinones, from a Marine Sponge, Induce Erythroid Differentiation in Human Chronic Myelogenous Leukemia, K562 Cells
• Reversing Effect of Agosterol A, a Spongean Sterol Acetate, on Multidrug Resistance in Human Carcinoma Cells
• 各種甘草含有成分のHPLCによる定量分析
• 甘草修治における成分変化 : 皮去り甘草と炙甘草中のサポニン及びフラボノイド成分の定量分析
• 日本産アカヤジオウとカイケイジオウの交配種フクチヤマジオウ根の含有成分
• インドネシア薬用植物第XXI報 : Erythrina variegata樹皮とMaclura cochinchinensis根から単離したNa+/H+交換阻害物質
• インドネシア薬用植物 第XVIII報 : Koompassia malaccensis(マメ科)樹皮から単離した新規スチルベン-フェニルプロパノイド、Kompasonol A(発表論文抄録(1997))
• インドネシア薬用植物 第XVII報 : Quassia indica枝から単離したカッシノイド類の解析(発表論文抄録(1997))
• 74 ねじれたπ電子共役系の円二色性と絶対構造 : 天然物への応用
• HETEROSIGMA-GLYCOLIPIDS I AND II, TWO NEW GALACTOLIPIDS CONTAINING OCTADECATETRAENOYL AND EICOSAPENTAENOYL RESIDUES, FROM A RAPHIDOPHYTE DINOFLAGELLATE HETEROSIGMA SP.
• Marine Natural Products. XX. : Bioactive Scalarane-Type Bishomosesterterpenes from the Okinawan Marine Sponge Phyllospongia foliascens
• Marine Natural Products. XIX. : Pervicosides A, B, and C, Lanostane-Type Triterpene-Oligoglycoside Sulfates from the Sea Cucumber Holothuria pervicax
• Marine Natural Products. XVIII. : Four Lanostane-Type Triterpene Oligoglycosides, Bivittosides A, B, C, and D, from the Okinawan Sea Cucumber Bohadschia bivittata MITSUKURI
• Marine Natural Products. XVII. Nephtheoxydiol, a New Cytotoxic Hydroperoxy-Germacrane Sesquiterpene, and Related Sesquiterpenoids from an Okinawan Soft Coral of Nephthea sp. (Nephtheidae)(Organic,Chemical)
• Marine Natural Products. XVI. : Structures of Five New Diterpenes from an Okinawan Soft Coral of Xenia sp. (Xeniidae)
• KERICEMBRENOLIDES A, B, C, D, AND E, FIVE NEW CYTOTOXIC CEMBRENOLIDES FROM THE OKINAWAN SOFT CORAL CLAVULARIA KOELLIKERI
• Marine Natural Products. XIV. Structures of Echinosides A and B, Antifungal Lanostane-Oligosides from the Sea Cucumber Actinopyga echinites (JAEGER)
• XENIOLONE AND ISOXENIOLONE TWO NEW DITERPENES HAVING A PERHYDROAZULENE SKELETON FROM AN OKINAWAN SOFT CORAL OF XENIA SP.
• HALENAQUINOL AND HALENAQUINOL SULFATE, PENTACYCLIC HYDROQUINONES FROM THE OKINAWAN MARINE SPONGE XESTOSPONGIA SAPRA
• CLAVUKERIN C, A NEW TRINOR-GUAIANE SESQUITERPENE HAVING A HYDROPEROXY FUNCTION, FROM THE OKINAWAN SOFT CORAL CLAVULARIA KOELLIKERI
• 30 沖縄サンゴ礁生物Clavularia属軟サンゴ2種の成分研究
• Marine Natural Products. XII. On the Chemical Constituents of the Okinawan Marine Sponge Hymeniacidon aldis
• CLAVUKERIN A, A NEW TRINOR-GUAIANE SESQUITERPENE FROM THE OKINAWAN SOFT CORAL CLAVULARIA KOELLIKERI
• ABSOLUTE STEREOSTRUCTURES OF CLAVIRIDENONE-A, -B, -C, AND -D FOUR PROSTANOIDS FROM THE OKINAWAN SOFT CORAL CLAVULARIA VIRIDIS
• THREE NEW ent-VALERENANE SESQUITERPENES FROM AN OKINAWAN SOFT CORAL
• Marine Natural Products. IX. Structural Elucidation of Triterpenoidal Oligoglycosides from the Bahamean Sea Cucumber Actinopyga agassizi SELENKA
• The Structures of Six Antifungal Oligoglycosides, Stichlorosides A_1,A_2,B_1,B_2,C_1,and C_2,from the Sea Cucumber Stichopus Chloronotus (BRANDT)
• Marine Natural Products. VIII. Bioactive Triterpene-Oligoglycosides from the Sea Cucumber Holothuria leucospilota BRANDT (2). Structure of Holethurin A
• Marine Natural Products. VII. Bioactive Triterpene-Oligoglycosides from the Sea Cucumber Holothuria leucospilota BRANDT (1). Structure of Holothurin B
• Major vault protein forms complexes with hypoxia-inducible factor (HIF)-1α and reduces HIF-1α level in ACHN human renal adenocarcinoma cells
• Marine Natural Products. XXVI. Biologically Active Tridecapeptide Lactones from the Okinawan Marine Sponge Theonella swinhoei(Theonellidae).(2).Structures of Theonellapeptolides Ia, Ib, Ic, and Ie
• Direct Identification of a Novel Disulfide Bond Linkage System of New Isolated Isomer (Isomer V) in Recombinantly Produced h-IGF-I
• Synthesis of Two Possible Disulfide Bonds Containing Peptide Fragments(Cys^6-Cys^, Cys^-Cys^(Type I), and Cys^6-Cys^, Cys^-Cys^(Type II) of h-IGF-I) for the Identification of Disulfide Bond Linkage in Recombinantly Produced h-IGF-I
• Synthetic Studies on Biological Active Peptides 4 Synthesis of Two Possible Disulfide Bond-Containing Fragments,Cys6-Cys47,Cys48-Cys52(Type 1)and Cys6-Cys48,Cys47-Cys52(Type 2)of h-IGF-1(4-9,47-53),for the Chemical Identification of the Disulfide Bond Lin
• 海洋天然物 第XXXIII報 : 沖縄産海綿Theonella swinhoeiの産生する新規テトラデカペプチドラクトンTheonellapeptolide IId(発表論文抄録(1994))
• Marine Natural Products. XXXIII. Theonellapeptolide IId, a New Tridecapeptide Lactone from the Okinawan Marine Sponge Theonella swinhoei
• Formation and Hydrolysis of Enamine in Aqueous Solution
• Haliclonacyclamines, Tetracyclic Alkylpiperidine Alkaloids, as Anti-dormant Mycobacterial Substances from a Marine Sponge of Haliclona sp.
• Pyripyropenes, Fungal Sesquiterpenes Conjugated with α-Pyrone and Pyridine Moieties, Exhibits Anti-angiogenic Activity against Human Umbilical Vein Endothelial Cells
• Prenylterphenyllin and Its Dehydroxyl Analogs, New Cytotoxic Substances from a Marine-derived Fungus Aspergillus candidus IF10
• Indonesian Medicinal Plants. XVII. Characterization of Quassinoids from the Stems of Quassia indica
• Marine Natural Products. XXXVI. Biologically Active Polyacetylenes, Adociacetylenes A, B, C, and D, from an Okinawan Marine Sponge of Adocia sp.
• Stichlorogenol and Dehydrostichlorogenol, Genuine Aglycones of Stichlorosides A_1,B_1,C_1 and A_2,B_2,C_2,from the Sea Cucumber Stichopus Chloronotus (BRANDT)
• インドネシア薬用植物 第VIII報 : Caesalpinia major(マメ科)根から単離した3種の新規カッサン型フラノジテルペンcaesaldekarin c, d,及びeの化学構造 : caesaldekarin aのN-ブロモスクシンイミド処理による数種の興味ある反応生成物(発表論文抄録(1997))
• THE ABSOLUTE STEREOSTRUCTURE OF ARENASTATIN A, A POTENT CYTOTOXIC DEPSIPEPTIDE FROM THE OKINAWAN MARINE SPONGE DYSIDEA ARENARIA
• IMPROVED TOTAL SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP OF ARENASTATIN A, A POTENT CYTOTOXIC SPONGEAN DEPSIPEPTIDE
• P-56 海綿Dysidea arenaria由来の抗腫瘍性デプシペプチドarenastatin A : 類縁体合成と活性(ポスター発表の部)
• A TOTAL SYNTHESIS OF ARENASTATIN A, AN EXTREMELY POTENT CYTOTOXIC DEPSIPEPTIDE, FROM THE OKINAWAN MARINE SPONGE DYSIDEA ARENARIA
• Obesity affects expression of progesterone receptors and node metastasis of mammary carcinomas in postmenopausal women without a family history
• Histological and biological characteristics of microinvasion in mammary carcinomas 【less than or equal】 2 cm in diameter
• Immunohistochemical studies on expression of human vascular smooth muscle myosin heavy chain isoforms in normal mammary glands, benign mammary disorders and mammary carcinomas
• Malformation of Immature Starfish Oocytes by Theonellapeptolide Ie, a Tridecapeptide Lactone from a Marine Sponge Petrosia Species, through Disturbance of Cortical F-Actin Distribution(Biochemistry & Molecular Biology)
• Novel Neuronal Nitric Oxide Synthase(nNOS)Selective Inhibitor, Aplysinopsin-Type Indole Alkaloid, from Marine Sponge Hyrtios erecta
• Marine Natural Products. XXXVII. Aragusteroketals A and C, Tow Novel Cytotoxic Steroids from a Marine Sponge of Xestospongia sp.
• Influence of N-Terminal Peptide and Oligosaccharide on the Clearance of t-PA
• Endogenous Tumor Necrosis Factor Inhibits the Cytotoxicity of Exogenous Tumor Necrosis Factor and Adriamycin in Pancreatic Carcinoma Cells
• Reversal of Tumor Necrosis Factor Resistance in Tumor Cells by Adriamycin via Suppression of Intracellular Resistance Factors
• Absorption of Ibuprofen Coated by Anhydrous Silicic Acid
• Stereostructure of Komodoquinone A, a Neuritogenic Anthracycline, from Marine Streptomyces sp. KS3
• Influence of Sugar Chain on Fibrin Affinity of Recombinat t-PA
• Marine Natural Products. XXXVIII. Absolute Stereostructures of Altohyrtins A, B, and C and 5-Desacetylaltohyrtin A, Potent Cytotoxic Macrolides, from the Okinawan Marine Sponge Hyrtios altum
• P-274 STRUCTURE-ACTIVITY RELATIONSHIP OF AGOSTEROL A, A MDR-REVERSING STEROL ACETATE FROM MARINE SPONGE
• Cytotoxicity of Neutrophil-Induced Superoxide to Isolated Pancreatic Acinar Cells
• P-84 NEUROPROTECTIVE EFFECT OF CRAMBESCIDIN 800 AGAINST OXIDATIVE NEURONAL TOXICITY

もっと見る 閉じる

スポンサーリンク