Stereostructure of Komodoquinone A, a Neuritogenic Anthracycline, from Marine Streptomyces sp. KS3

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概要

• 論文の詳細を見る

• The absolute Stereostructure of komodoquinone A (1), a neuritogenic anthracycline, which was isolated from a cultured marine Streptomyces sp. KS3, has been determined on the basis of chemical derivatization. Komodoquinone A (1) induces neuronal cell differentiation in the neuroblastoma cell line, Neuro 2A and arrests the cell cycle at the G1 phase. The effect of a solid-state medium on the production of 1 and its aglycone, komodoquinone B (2), was examined.

• 公益社団法人日本薬学会の論文
• 2003-12-01

著者

• 伊藤 喬

  昭和大学薬学部

• KOBAYASHI Motomasa

  Graduate School of Pharmaceutical Sciences, Osaka University

• ITOH Takuya

  Graduate School of Pharmaceutical Sciences, Osaka University

• 伊藤 喬

  昭和大学薬学部薬化学教室

• Itoh T

  Graduate School Of Pharmaceutical Sciences Osaka University

• Itoh Takuya

  Graduate School Of Pharmaceutical Sciences Osaka University

• Itoh Tatsuya

  Faculty Of Pharmaceutical Sciences Hokuriku University

• Wei Hong

  Graduate School of Pharmaceutical Sciences, Osaka University

• Wei Hong

  Graduate School Of Pharmaceutical Sciences Osaka University

• Kobayashi M

  Fujisawa Pharmaceutical Co. Ltd. :(peresent Address)fujisawa Research Insitute Of America Inc. North

• Kobayashi M

  Faculty Of Pharmaceutical Sciences Osaka University

• Kobayashi Masao

  Pharmaceutical Research Laboratory Tanabe Seiyaku Co. Ltd.

• Kobayashi M

  Graduate School Of Pharmaceutical Sciences Osaka University

• Wei H

  Graduate School Of Pharmaceutical Sciences Osaka University

• KINOSHITA Masahiro

  Graduate School of Pharmaceutical Sciences, Osaka University

• 小林 資正

  Graduate School Of Pharmaceutical Sciences Osaka University

• Kinoshita M

  Graduate School Of Pharmaceutical Sciences Osaka University

• Kobayashi Motomasa

  Graduate School Of Pharmaceutical Sciences Osaka Univ.

• Kawaguchi M

  Graduate School Of Pharmaceutical Sciences Osaka University

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