Marine Natural Products. XX. : Bioactive Scalarane-Type Bishomosesterterpenes from the Okinawan Marine Sponge Phyllospongia foliascens
スポンサーリンク
概要
- 論文の詳細を見る
Two new scalarane-type bishomosesterterpenes, dehydrofoliaspongin (17) and phyllofoliaspongin (18), were isolated together with foliaspongin (4) and scalardysin-B (15) from the Okinawan marine sponge Phyllospongia foliascens. On the basis of chemical and physicochemical evidence including the X-ray crystallographic analysis of a methylated derivative (16) of 15,the structures of 17 and 18 were determined and the previously proposed structure (3) of foliaspongin was revised to 4,having a 4β-ethyl moiety. Phyllofoliaspongin (18) showed cytotoxic, anti-thrombocyte, and vasodilative activities.
- 社団法人日本薬学会の論文
- 1989-08-25
著者
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北川 勲
Faculty of Pharmaceutical Sciences, Osaka University
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小林 資正
Faculty of Pharmaceutical Sciences, Osaka University
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京極 好正
Institute for Protein Research, Osaka University
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李 南庚
Faculty of Pharmaceutical Sciences, Osaka University
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京極 好正
阪大・蛋白研
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京極 好正
大阪大学蛋白質研究所
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京極 好正
Institute For Protein Research Osaka University
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京極 好正
群馬大学内分泌研究所
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北川 勲
Faculty Of Pharmaceutical Sciences Osaka University
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李 南庚
Faculty Of Pharmaceutical Sciences Osaka University
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小山 嘉晃
Suntory Institute for Biomedical Research
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Kobayashi M
Fujisawa Pharmaceutical Co. Ltd. :(peresent Address)fujisawa Research Insitute Of America Inc. North
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Kobayashi M
Faculty Of Pharmaceutical Sciences Osaka University
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