Marine Natural Products. XVII. Nephtheoxydiol, a New Cytotoxic Hydroperoxy-Germacrane Sesquiterpene, and Related Sesquiterpenoids from an Okinawan Soft Coral of Nephthea sp. (Nephtheidae)(Organic,Chemical)

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概要

• 論文の詳細を見る

• A new cytotoxic hydroperoxy-germacrane sesquiterpene named nephtheoxydioi (8) and several related sesquiterpenoids, ent-oplopanone (2), nephthenol (6), and nephthediol (9), were isolated from an Okinawan soft coral of Nephthea sp. (Nephtheidae), together with a new cadinanetype sesquiterpene named nephthene (17). Based on chemical reactions and physical data analyses, the absolute stereostructures of ent-oplopanone (2). nephthenol (6), nephtheoxydiol (8). nephthediol (9), and nephthene (17) have been determined as (+)-oplopanone (2), (4R,7S)-germacra1(10)E,5E-dien-4-ol (6), (1S,4R,7S)-1-hydroperoxygermacra-5E,10(15)-dien-4-ol (8), (1S,4R,7S)-germacra-5E,10(15)-diene-1,4-diol (9), and (1S.7R,10S)-cadina-4(14),5-diene (17), respectively.

• 社団法人日本薬学会の論文
• 1987-01-25

著者

• 北川 勲

  Faculty of Pharmaceutical Sciences, Osaka University

• 小林 資正

  Faculty of Pharmaceutical Sciences, Osaka University

• 京極 好正

  Institute for Protein Research, Osaka University

• 京極 好正

  阪大・蛋白研

• 京極 好正

  大阪大学蛋白質研究所

• 京極 好正

  Institute For Protein Research Osaka University

• 京極 好正

  群馬大学内分泌研究所

• 北川 勲

  Faculty Of Pharmaceutical Sciences Osaka University

• 孫 炳華

  Faculty of Pharmaceutical Sciences, Osaka University

• 崔 征

  Faculty of Pharmaceutical Sciences, Osaka University

• Kobayashi M

  Fujisawa Pharmaceutical Co. Ltd. :(peresent Address)fujisawa Research Insitute Of America Inc. North

• Kobayashi M

  Faculty Of Pharmaceutical Sciences Osaka University

• 孫 炳華

  Faculty Of Pharmaceutical Sciences Osaka University

• 崔 征

  Faculty Of Pharmaceutical Sciences Osaka University

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