STRUCTURE OF THEONELLAPEPTOLIDE ID, A NEW BIOACTIVE PEPTOLIDE FROM AN OKIKAWAN MARINE SPONGE, THEONELLA SP. (THEONELLIAE)

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概要

• 論文の詳細を見る

• A new peptolide named theonellapeptolide Id (1___〜) has been isolated from an Okinawan marine sponge of Theonella sp. (Theonelliae) together with some minor peptolides (theonellapeptolides Ia, Ib, Ic, and Ie).These peptolides inhibit development of the fertilized eggs of the sea urchin Hemicentrotus pulcherrimus. The structure of theonellapeptolide Id (1___〜) has been determined on the basis of chemical and physico-chemical evidence. Theonellapeptolide Id (1___〜) is rare example of a peptolide characteristically comprising N-methyl and D amino acids in high ratio.

• 社団法人日本薬学会の論文
• 1986-06-25

著者

• 北川 勲

  Faculty of Pharmaceutical Sciences, Osaka University

• 小林 資正

  Faculty of Pharmaceutical Sciences, Osaka University

• 河田 康志

  Institute For Protein Research Osaka University

• 李 南庚

  Faculty of Pharmaceutical Sciences, Osaka University

• 渋谷 博孝

  Faculty of Pharmaceutical Sciences, Osaka University

• 崎山 文夫

  Institute for Protein Research, Osaka University

• 北川 勲

  Faculty Of Pharmaceutical Sciences Osaka University

• 李 南庚

  Faculty Of Pharmaceutical Sciences Osaka University

• Kobayashi M

  Fujisawa Pharmaceutical Co. Ltd. :(peresent Address)fujisawa Research Insitute Of America Inc. North

• Kobayashi M

  Faculty Of Pharmaceutical Sciences Osaka University

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