A General Synthesis of (±)-Dibenzocyclooctadiene Lignans
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概要
- 論文の詳細を見る
We have established a new general synthesis for (±)-dibenzocyclooctadiene lignans, including (±)-schizandrin (1a), (±)-gomisin A (1b), (±)-isoschizandrin (3a), and (±)-isogomisin A (3b), via the spiro-dienone ethers E- and T-11 as the key intermediates, prepared from the corresponding bisarylbutanol derivatives E- and T-10 by the oxidation with Weitz' aminium salt, tris(4-bromophenyl)aminium hexachloroantimonate (BAHA). These syntheses consist of 13 steps from the phenylpropanone 5.
- 公益社団法人日本薬学会の論文
- 1996-05-15
著者
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伊藤 喬
昭和大学薬学部薬化学教室
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TAKEYA Tetsuya
Showa College of Pharmaceutical Sciences
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YAMAKI Shinobu
Showa College of Pharmaceutical Sciences
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ITOH Toshimasa
Showa College of Pharmaceutical Sciences
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HOSOGAI Hiroko
Showa College of Pharmaceutical Sciences
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TOBINAGA Seisho
Showa College of Pharmaceutical Sciences
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Takeya T
Showa Pharmaceutical University
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Tobinaga S
Showa Pharmaceutical University
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Yamaki S
Showa College Of Pharmaceutical Sciences
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