Indonesian Medicinal Plants. VIII. Chemical Structures of Three New Triterpenoids, Bruceajavanin A, Dihydrobruceajavanin A, and Bruceajavanin B, and a New Alkaloidal Glycoside, Bruceacanthinoside, from the Stems of Brucea javanica (Simaroubaceae)

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概要

• 論文の詳細を見る

• Three new apotirucallane-type triterpenoids named bruceajavanin A (1) dihydrobruceajavanin A (2), and bruceajavanin B (3), and a novel β-carboline alkaloidal glycoside named bruceacanthinoside (4) were isolated from the stems of Brucea javanica (Simaroubaceae), a traditional medicine used to treat malaria in the Bengkulu area, Sumatra, Indonesia. Their chemical structures have been elucidated on the bases of their chemical and physicochemical properties. Bruceajavanin A (1), dihydrobruceajavanin A (2) and bruceacanthinoside (4) were shown to inhibit growth of the cultured malarial parasite Plasmodium falciparum K1 of a chloroquine-resistant strain.

• 公益社団法人日本薬学会の論文
• 1994-07-15

著者

• 北川 勲

  Faculty of Pharmaceutical Sciences, Osaka University

• 渋谷 博孝

  福山大学

• 渋谷 博孝

  Faculty of Pharmaceutical Sciences, Osaka University

• 堀 一之

  大阪大学薬学部

• 堀 一之

  Faculty of Pharmaceutical Sciences, Osaka University

• シマンジュンタク パルトムアン

  大阪大学薬学部

• SIMANJUNTAK Partomuan

  Faculty of Pharmaceutical Sciences, Osaka University

• 北川 勲

  大阪大学

• 北川 勲

  Faculty Of Pharmaceutical Sciences Osaka University

• UJI Tahan

  Herbarium Bogoriense, Pusat Penelitian dan Pengembangan Biologi-LIPI

• MAHMUD Taifo

  Faculty of Pharmaceutical Sciences, Osaka University

• Uji T

  Herbarium Bogoriense Research And Development Centre For Biology Lipi

• マフムド タイフォ

  大阪大学薬学部

• Momose T

  大阪大学薬学部

• Mahmud Taifo

  Faculty Of Pharmaceutical Sciences Osaka University

• Simanjuntak P

  Osaka Univ. Osaka Jpn

• Simanjuntak Partomuan

  Research Center For Biotechnology Indonesian Institute Of Sciences

• Simanjuntak Partomuan

  Faculty Of Pharmaceutical Sciences Osaka University

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