Citronellol and Geraniol, Components of Rose Oil, Activate Peroxisome Proliferator-Activated Receptor α and γ and Suppress Cyclooxygenase-2 Expression

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概要

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• We evaluated the effects of rose oil on the peroxisome proliferator-activated receptor (PPAR) and cyclooxygenase-2 (COX-2). Citronellol and geraniol, the major components of rose oil, activated PPARα and γ, and suppressed LPS-induced COX-2 expression in cell culture assays, although the PPARγ-dependent suppression of COX-2 promoter activity was evident only with citronellol, indicating that citronellol and geraniol were the active components of rose oil.

• 2011-05-23

著者

• Hiwatashi Kazuyuki

  秋田県農林水産技術センター総合食品研究所

• Hiwatashi Kazuyuki

  東北大学 農学研究科栄養学

• Takahashi S

  Akita Res. Inst. Food And Brewing Akita Jpn

• Takahashi S

  Kyoto Univ. Kyoto Jpn

• Inoue Hiroyasu

  Department Of Food Science And Nutrition Nara Women's University

• Takahashi S

  Department Of Biosciences Teikyo University

• Kojima Hiroaki

  R & D Company Kobayashi Pharmaceutical Co. Ltd.

• Takahashi S

  Akita Res. Inst. Of Food And Brewing

• Takahashi Saori

  Akita Res. Inst. Of Food And Brewing

• Takahashi S

  Akita Res. Inst. Food And Brewing Akita

• Takahashi Shunji

  Institute Of Molecular And Cellular Biosciences University Of Tokyo

• Takahashi Shunji

  Department Of Bioresources Chemistry Faculty Of Horticulture Chiba University

• Inoue Hiroyasu

  Department Of Applied Chemistry Faculty Of Technology Kanagawa University

• Inoue Hiroyasu

  Department Of Food Science And Nutrition Faculty Of Human Life And Environment Nara Women's Uni

• HORI Kazuyuki

  Department of Bioengineering, Akita Research Institute of Food and Brewing (ARIF)

• Hori K

  Kao Co. Ltd. Tochigi Jpn

• Hori Kazuyuki

  The Central Research Laboratory Hitachi Ltd.

• Nakata Rieko

  Department Of Food Science And Nutrition Nara Women's University

• Suzuki Takahito

  Biological Laboratory Faculty Of Science Nara Women's University

• Takahashi Saori

  Department Of Applied Biology Faculty Of Textile Science Kyoto Institute Of Technology

• Takahashi S

  Department Of Biology The University Of Tokyo

• KATSUKAWA Michiko

  Department of Food Science and Nutrition, Nara Women's University

• KOEJI Satomi

  Department of Food Science and Nutrition, Nara Women's University

• Koeji Satomi

  Department Of Food Science And Nutrition Nara Women's University

• Katsukawa Michiko

  Department Of Food Science And Nutrition Nara Women's University

• Hori Kazuyuki

  Department Of Bioengineering Akita Research Institute Of Food And Brewing

• Takahashi Satoru

  Institute Of Basic Medical Sceinces And Center For Tara

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