Horseradish Peroxidase Degrades Lipid Hydroperoxides and Suppresses Lipid Peroxidation of Polyunsaturated Fatty Acids in the Presence of Phenolic Antioxidants(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
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概要
- 論文の詳細を見る
Linoleic acid hydroperoxide (LAOOH) was effectively degraded by horseradish peroxidase (HRP) in the presence of quercetin. Several natural phenolic antioxidants, such as quercetin, capsaicin, and α-tocopherol, acted as good hydrogen donors in the peroxidase reaction that occurs during lipid hydroperoxide degradation. However, glutathione, which is a non-phenolic antioxidant that acts as a hydrogen donor for glutathione peroxidase, could not suppress lipid peroxidation in the presence of HRP. Lipid hydroperoxides generated from eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) were also degraded with HRP in the presence of quercetin, and oxidative decomposition of DHA was suppressed by this reaction.
- 社団法人日本生物工学会の論文
- 2005-12-25
著者
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SATO Keiko
Department of Molecular Biology-Institute of Gerontology and Department of Internal Medicine II, Nip
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SHIRASAKA Norifumi
Department of Agricultural Chemistry, Faculty of Agriculture, Kyoto University
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TERASHITA Takao
Department of Food and Nutrition, Faculty of Agriculture, Kinki University
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YOSHIZUMI Hajime
Department of Food and Nutrition, Faculty of Agriculture, Kinki University
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Shirasaka N
Kinki Univ. Nara Jpn
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Shirasaka Norifumi
Department Of Food Science And Nutrition Faculty Of Agriculture Kinki University
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Shirasaka Norifumi
近畿大学 農学部
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Shirasaka Norifumi
Department Of Applied Biological Chemistry Faculty Of Agriculture Kin-ki University
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Shirasaka Norifumi
Department Of Agricultural Chemistry Kyoto University
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MIYAMOTO Rie
Department of Restorative Dentistry and Endodontology, Kagoshima University Graduate School of Medic
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Ohnishi Hiromichi
Department of Food and Nutrition, Faculty of Agriculture, Kin-ki University
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Yoshizumi Hajime
Institute For Fundamental Research Research Center
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Yoshizumi Hajime
Department Of Food And Nutrition Faculty Of Agriculture Kin-ki University
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Ohnishi Hiromichi
Department Of Cardiology Kagawa Prefectural Central Hospital
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Ohnishi Hiromichi
Department Of Food And Nutrition Faculty Of Agriculture Kin-ki University
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Miyamoto Rie
Department Of Food And Nutrition Faculty Of Agriculture Kin-ki University
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Miyamoto Rie
Department Of Agricultural And Biological Chemistry College Of Bioresource Sciences Nihon University
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Terashita Takao
Department Of Agricultural Chemistry College Of Agriculture University Of Osaka Prefecture
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Terashita Takao
Department Of Applied Biological Chemistry Faculty Of Agriculture Kin-ki University
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Sato Keiko
Department Of Molecular Biology-institute Of Gerontology And Department Of Internal Medicine Ii Nipp
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Sato Keiko
Department Of Epidemiology And Health Care Research Graduate School Of Medicine And Public Health Ky
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Sato Keiko
Department Of Food And Nutrition Faculty Of Agriculture Kin-ki University
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