Citric Acid Production by Surface Culture Using Aspergillus niger : Kinetics and Simulation
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概要
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The citric acid production rate for batch surface culture using Aspergillus niger Yang no. 2 was examined experimentally in terms of rate coefficients and the effect of various depths of medium. The citric acid production rate was affected by the biofilm mass expressed as mg-Cell/cm^2-film. The biofilm mass increased in parallel with medium depth. The citric acid production rate divided by the biomass weight at the end of cultivation was constant when the biofilm mass was less than 40 mg/cm^2,but decreased above this critical value. The citric acid fermentation time course was expressed by the Luedeking-Piret type rate expression. The time course of the surface cultivation was simulated well with the expression when biofilm mass was less than 40 mg/cm^2. In this range, rate coefficients were obtained by the nonlinear least squares method. Comparison in regard to the citric acid productivity between surface and other types of cultures in the literatures was made.
- 社団法人日本生物工学会の論文
- 1991-07-25
著者
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Usami Shoji
Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima Uni
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IMAI Hiroshi
Departments of Cardio-angiology and Emergency and Critical Care Medicine, Kitasato University School
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Endoh Kazuo
Department Of Atomic Science And Nuclear Engineering Faculty Of Engineering Hokkaido University
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Usami Shoji
Department Of Applied Chemistry Faculty Of Science And Engineering Waseda University
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SAKURAI AKIHIKO
Department of chemical Process Engineering, Faculty of Engineering, Hokkaido University
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EJIRI TETSUO
Department of Chemical Process Engineering, Faculty of Engineering, Hokkaido University
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Ejiri Tetsuo
Department Of Chemical Process Engineering Faculty Of Engineering Hokkaido University
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Sakurai A
Fukui Univ. Fukui Jpn
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Sakurai Akihiko
Department Of Applied Chemistry And Biotechnology Faculty Of Engineering Fukui University
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Imai Hiroshi
Departments Of Cardio-angiology And Emergency And Critical Care Medicine Kitasato University School
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Imai Hiroshi
Department Of Biological Sciences Graduate School Of Science University Of Tokyo
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